This book focusses on the development of biomedical membranes and their applications for (bio)artificial organs. It covers the state of art and main challenges for applying synthetic membranes in these organs. It also highlights the importance of accomplishing an integration of engineering with biology and medicine to understand and manage the scientific, industrial, clinical and ethical aspects of these organs.The compendium consists of 11 chapters, written by world renowned experts in the fields of membrane technology, biomaterials science and technology, cell biology, medicine and engineering. Every chapter describes the clinical needs and the materials, membranes, and concepts required for the successful development of the (bio)artificial organs.This text is suitable for undergraduate and graduate students in biomedical engineering, materials science and membrane science and technology, as well as, for professionals and researchers working in these fields.

This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.

A Cutting-Edge Guide to Applying Transport Phenomena Principles to Bioengineering Systems Transport Phenomena in Biomedical Engineering: Artificial Order Design and Development and Tissue Engineering explains how to apply the equations of continuity, momentum, energy, and mass to human anatomical systems. This authoritative resource presents solutions along with term-by-term medical significance. Worked exercises illustrate the equations derived, and detailed case studies highlight real-world examples of artificial organ design and human tissue engineering. Coverage includes: Fundamentals of fluid mechanics and principles of molecular diffusion Osmotic pressure, solvent permeability, and solute transport Rheology of blood and transport Gas transport Pharmacokinetics Tissue design Bioartificial organ design and immunoisolation Bioheat transport 541 end-of-chapter exercises and review questions 106 illustrations 1,469 equations derived from first principles

This text combines the basic principles and theories of transport in biological systems with fundamental bioengineering. It contains real world applications in drug delivery systems, tissue engineering, and artificial organs. Considerable significance is placed on developing a quantitative understanding of the underlying physical, chemical, and biological phenomena. Therefore, many mathematical methods are developed using compartmental approaches. The book is replete with examples and problems.

Integrated Membrane Reactors explores recent developments and future perspectives in the area of membrane reactor (MR) systems. It includes fundamental principles, the different types of membrane materials (such as polymeric and inorganic), the different types of membrane reactors (such as Micro MRs, Enzymatic MRS, Photo-catalytic MRs, Pervaporation MRs, Electrochemical MRs, etc.), their industrial perspective and, finally, there also is an economic evaluation of the metallic MRs. The book provides an extensive review in the area of MRs for each kind of application present in the specialized literature and discusses their modelling and design approaches necessary for MR systems validation in achieving high conversions, energy savings, high yields and high hydrogen (or others) products of the reactions studied. - Includes membrane preparation and characterization - Describes all the kinds of membrane reactors today under study - Focuses on many applications of membrane reactors in the area of chemical and biochemical engineering - Discusses simulation of membrane reactors enabling their design - Introduces the concepts of process intensification and process integration - Illustrates all the advantages of membrane reactors with respect to the so-called traditional/convention reactor

An important resource that puts the focus on the chemical engineering aspects of biomedical engineering In the past 50 years remarkable achievements have been advanced in the fields of biomedical and chemical engineering. With contributions from leading chemical engineers, Biomedical Engineering Challenges reviews the recent research and discovery that sits at the interface of engineering and biology. The authors explore the principles and practices that are applied to the ever-expanding array of such new areas as gene-therapy delivery, biosensor design, and the development of improved therapeutic compounds, imaging agents, and drug delivery vehicles. Filled with illustrative case studies, this important resource examines such important work as methods of growing human cells and tissues outside the body in order to repair or replace damaged tissues. In addition, the text covers a range of topics including the challenges faced with developing artificial lungs, kidneys, and livers; advances in 3D cell culture systems; and chemical reaction methodologies for biomedical imagining analysis. This vital resource: Covers interdisciplinary research at the interface between chemical engineering, biology, and chemistry Provides a series of valuable case studies describing current themes in biomedical engineering Explores chemical engineering principles such as mass transfer, bioreactor technologies as applied to problems such as cell culture, tissue engineering, and biomedical imaging Written from the point of view of chemical engineers, this authoritative guide offers a broad-ranging but concise overview of research at the interface of chemical engineering and biology.

Membrane techniques are an excellent alternative to traditional methods of purification and separation. This book covers issues related to the most recent developments in the field of membrane techniques. The latest scientific research and their potential applications in industrial solutions are described. In addition, currents trends in food & beverages technologies, and biomedicine are discussed. Moreover, the book emphasizes recent advancements in design of membrane systems, used either for separation or creation of mixtures, from the perspective of industry 4.0 and data management.