Biomedical Applications of Polarimetry
Title | Biomedical Applications of Polarimetry PDF eBook |
Author | Nathaniel Owen King |
Publisher | |
Pages | 0 |
Release | 2020 |
Genre | |
ISBN |
Non- or minimally-invasive data collection is highly desirable for gathering the broad base of information that facilitates moving technology to the point of care. Polarimetry has been making this transition for years. Early forms of polarization-sensitive optics involved custom multiplexing a series of images to generate a single image, but today's snapshot polarimeters are readily commercially available.The research presented in this dissertation advances three areas of polarimetric imaging: First, this research develops a reflectance-based measurement for tracking changes in the alignment of dynamically loaded soft tissue, specifically tendon. This work highlights a range of mounting angles across which signal strength is agnostic to sensor location. Second, it compares a high dynamic range division-of-focal-plane (DoFP) polarimeter with a standard DoFP polarimeter, highlighting both the current limitations of polarimetry and future areas for sensor improvement. The incorporation of a DoFP polarization filter with a high dynamic range sensor represents an important advance in DoFP polarimetry, in that the high-dynamic range pixels can compensate for the reduced photon flux at the photosensor caused by the nano-wire filters. Finally, this research identifies a polarization-based neural signal, with major implications for non-invasively tracking neural activity, including the first tandem recording of optical and electrical activity from a single region. In conclusion, this work makes important advances across a range of polarimetric applications.
Optical Polarization in Biomedical Applications
Title | Optical Polarization in Biomedical Applications PDF eBook |
Author | Valery V. Tuchin |
Publisher | Springer Science & Business Media |
Pages | 281 |
Release | 2006-10-12 |
Genre | Science |
ISBN | 3540453210 |
Optical Polarization in Biomedical Applications introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues. This theory uses the modified transfer equation for Stokes parameters and predicts the polarization structure of multiple scattered optical fields. The backscattering polarization matrices (Jones matrix and Mueller matrix) important for noninvasive medical diagnostic are introduced. The text also describes a number of diagnostic techniques such as CW polarization imaging and spectroscopy, polarization microscopy and cytometry. As a new tool for medical diagnosis, optical coherent polarization tomography is analyzed. The monograph also covers a range of biomedical applications, among them cataract and glaucoma diagnostics, glucose sensing, and the detection of bacteria.
Optical Polarimetric Modalities for Biomedical Research
Title | Optical Polarimetric Modalities for Biomedical Research PDF eBook |
Author | Nirmal Mazumder |
Publisher | Springer Nature |
Pages | 455 |
Release | 2023-07-25 |
Genre | Science |
ISBN | 3031318528 |
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.
Polarized Light in Biomedical Imaging and Sensing
Title | Polarized Light in Biomedical Imaging and Sensing PDF eBook |
Author | Jessica C. Ramella-Roman |
Publisher | Springer Nature |
Pages | 362 |
Release | 2022-11-14 |
Genre | Technology & Engineering |
ISBN | 3031047419 |
This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.
Biomedical Applications of Polarimetric Imaging Contrast. Initial Studies for Scattering Media and Human Tissues
Title | Biomedical Applications of Polarimetric Imaging Contrast. Initial Studies for Scattering Media and Human Tissues PDF eBook |
Author | Maria Rosaria Antonelli |
Publisher | |
Pages | 146 |
Release | 2011 |
Genre | |
ISBN |
Liquid Crystals: Frontiers In Biomedical Applications
Title | Liquid Crystals: Frontiers In Biomedical Applications PDF eBook |
Author | Gregory P Crawford |
Publisher | World Scientific |
Pages | 514 |
Release | 2007-08-13 |
Genre | Technology & Engineering |
ISBN | 981447603X |
The confluence of the fields of liquid crystals and biomedical engineering is resulting in remarkable interdisciplinary research. This book focuses on the potential for inherently translational research in one field of engineering to radically alter the scope of another. The text reviews the exciting advances being made in displays, spectroscopy, sensors and diagnostics, biomimicking, actuators and lasers with regards to liquid crystalline materials, and biomedicine. The liquid crystal field — which has delivered revolutionary devices in the display, optics, and telecommunications industries — is now poised to make significant inroads into biology, medicine, and biomedical engineering.
Advanced Photonics Methods for Biomedical Applications
Title | Advanced Photonics Methods for Biomedical Applications PDF eBook |
Author | Edik Rafailov |
Publisher | CRC Press |
Pages | 227 |
Release | 2023-07-31 |
Genre | Technology & Engineering |
ISBN | 1000880052 |
Advanced photonics methods for biomedical applications give researchers in universities and industries, and clinicians an overview of the novel tools for cancer diagnostics and treatment. This book provides researchers and professionals in the area of biomedical photonics with a toolbox of novel methodologies for biomedical applications, including health diagnostics, cancer detection, and treatment. It covers the theory, modeling, and design of each method, alongside their applications, fabrication, characterization, and measurements in clinical practice. A wide scope of concepts concerning innovative science and technologies of medicine will be covered, providing the readers with the latest research, developments, and technologies. It will also be a valuable resource for students and early-career researchers, alongside those involved in the design of the novel photonics-based techniques for health diagnostics and cancer detection and treatment. Key features • Discusses novel methods of cancer diagnostics and cancer treatment. • Details non and minimally invasive photonics techniques. • Explores the applications of machine learning and artificial intelligence to these novel techniques.