Biomarkers of the Tumor Microenvironment

Biomarkers of the Tumor Microenvironment
Title Biomarkers of the Tumor Microenvironment PDF eBook
Author Lars A. Akslen
Publisher Springer
Pages 537
Release 2017-08-02
Genre Medical
ISBN 331939147X

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This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.

Biomarkers for Immunotherapy of Cancer

Biomarkers for Immunotherapy of Cancer
Title Biomarkers for Immunotherapy of Cancer PDF eBook
Author Magdalena Thurin
Publisher Humana
Pages 0
Release 2019-09-10
Genre Medical
ISBN 9781493997725

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This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy. The editors secured the input from experts in the field dedicated to translating scientific research from bench to bedside was submitted. The book provides not only details about the technical, standardization and interpretation aspects of the methods but also introduces the reader to the background information and scientific justification for selected biomarkers and assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Biomarkers of the Tumor Microenvironment

Biomarkers of the Tumor Microenvironment
Title Biomarkers of the Tumor Microenvironment PDF eBook
Author Lars A. Akslen
Publisher Springer Nature
Pages 596
Release 2022-07-12
Genre Medical
ISBN 303098950X

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This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.

Frontiers of Engineering

Frontiers of Engineering
Title Frontiers of Engineering PDF eBook
Author National Academy of Engineering
Publisher National Academies Press
Pages 125
Release 2019-02-28
Genre Technology & Engineering
ISBN 0309487501

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This volume presents papers on the topics covered at the National Academy of Engineering's 2018 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2018 symposium was held September 5-7 and hosted by MIT Lincoln Laboratory in Lexington, Massachusetts. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.

Histopathology

Histopathology
Title Histopathology PDF eBook
Author Supriya Srivastava
Publisher BoD – Books on Demand
Pages 168
Release 2018-09-19
Genre Medical
ISBN 178923686X

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This book, "Histopathology-An Update" is a comprehensive book that deals with the latest advances in the field of histopathology. This book will be of help to pathologists, clinicians and researchers in the latest update in histopathology of various organs.

The Link Between Inflammation and Cancer

The Link Between Inflammation and Cancer
Title The Link Between Inflammation and Cancer PDF eBook
Author Angus G. Dalgleish
Publisher Springer Science & Business Media
Pages 260
Release 2006-03-05
Genre Medical
ISBN 0387262830

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A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.

Ovarian Cancer Biomarkers

Ovarian Cancer Biomarkers
Title Ovarian Cancer Biomarkers PDF eBook
Author Khalid El Bairi
Publisher Springer Nature
Pages 236
Release 2021-10-09
Genre Medical
ISBN 9811618739

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This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.