This book is a printed edition of the Special Issue Bioactive and Therapeutic Dental Materials that was published in Materials

Bioactive materials, or biomaterials, have the ability to interact biologically with the tissue to which it is inserted, and to stimulate the deposition of mineralized tissue. The calcium phosphate-based ceramics were the first known materials in dentistry to have bioactivity, and currently, these materials are the most used for biomedical purposes, with different morphological characteristics. In dentistry, these materials have achieved immense importance by stimulating the deposition of osseous tissue in injured bone, and by having the ability to remineralize hard tooth tissues (enamel and dentin). Furthermore, repair materials based on aggregated trioxides mineral or on calcium hydroxide are classic biomaterials and widely used in dentistry, mainly in contact with the pulp tissue or periodontal ligament, for repair processes. However, various formulations of these materials appear all the time, in search of the ideal material. In general, bioactive materials have been shown to promote the release of calcium, sodium, silicon and phosphate ions, which are metabolized by the body, having effects such as angiogenesis and antimicrobial action, which can be improved depending on the composition of the material. Pulp tissue is a highly specialized dental tissue and is the subject of intense studies about the response to biomaterials. It is also understood that some systemic alterations in individuals have an influence on the action of bioactive materials during tissue repair processes. Thus, this book will address the use of different bioactive materials in dentistry, considering the performance of these biomaterials in the hard tissues of the tooth, and the response of the dental pulp, as well as the influence of the composition of these materials and of the individual's systemic alterations in bioactivity and in antimicrobial activity. The several in vivo and in vitro tests to evaluate the bioactivity of a biomaterial will also be addressed.

Restorative biomaterials in dentistry are designed to restore the shape and function of teeth. Their applicability is related to restorative procedures such as dental restorations, dentures, dental implants, and endodontic materials. Designing Bioactive Polymeric Materials for Restorative Dentistry reviews the current state of the art for restorative biomaterials and discusses the near-future trends in this field. The book examines the biomaterials utilized in restorative dental applications (bonding, composites, cements, and ceramics) and assesses the design for these materials and the role of nanotechnology. All of the contributors are active clinical dentists and researchers in this field. FEATURES Overviews the major ongoing research efforts on developing bioactive bonding systems and composites in dental biomaterials Focuses on emerging trends in restorative dental biomaterials Incorporates evidence-based data on new restorative dental materials throughout the book Features extensive references at the end of each chapter to enhance further study Mary Anne S. Melo, DDS, MSc, PhD FADM, is an Associate Professor and Division Director of Operative Dentistry at the School of Dentistry, University of Maryland, Baltimore, Maryland.

This book is a comprehensive guide to BiodentineTM, an innovative biocompatible and bioactive material based on pure tricalcium silicate that can permanently replace dentin and can also serve as a temporary enamel substitute. Although BiodentineTM has been widely used across the world for the past decade, this is the first book to be devoted to its properties, interactions with the soft and hard tissues, and its multiple clinical applications. The coverage encompasses applications in primary and permanent teeth, in specialties as diverse as restorative dentistry, endodontics, paediatric dentistry, dental traumatology, and prosthetic dentistry. BiodentineTM application both in vital pulp therapy and endodontic procedures is illustrated and clinical step by step protocols are provided. The book provides a detailed update on BiodentineTM use to preserve the pulp vitality in direct/indirect pulp capping, pulpotomy and irreversible pulpitis treatment. It also details BiodentineTM use for non-vital teeth treatment in indications such as root/furcation perforation repair, apexification as well as in regenerative endodontic procedures. BiodentineTM: Properties and Clinical Applications will be a rich source of guidance and information for all dentists as well as dental students and academics.

Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry. - Provides a comprehensive review of the materials science, engineering principles and recent advances in dental biomaterials - Reviews the fundamentals of dental biomaterials and examines advanced materials' applications for tissues regeneration and clinical dentistry - Written by an international collaborative team of materials scientists, biomedical engineers, oral biologists and dental clinicians in order to provide a balanced perspective on the field