'One of the best accounts ever written of deep-water diving and its staggering, haunting dangers' Robert Kurson, New York Times bestselling author of Shadow Divers Deep underwater lurks a mysterious man-made illness. It has gone by many names over the years – Satan’s disease, diver’s palsy, the chokes – but today, medics call it decompression sickness. You know it as the bends. That’s the devil British diver Martin Robson faces each time he plunges beneath the surface. In the winter of 2012, Robson was part of an expedition to Blue Lake, southern Russia, which sought to find a submerged cave system never seen by the human eye. On the final day of the expedition, as Robson returned from diving deeper into the lake than anyone had before, disaster struck: just seventy-five feet down, he was ambushed by the bends. Robson knew that if he continued up to the surface he would probably die before help arrived. Instead, he sank back into the water, gambling on an underwater practice most doctors believe is a suicidal act. Soon the only hope he had of saving his life would rest in the hands of a dramatic mercy mission organised at the highest levels of the Russian government. Between the Devil and the Deep is the first book to tell the terrifying true story of what it feels like to get the bends, taking you inside the body and mind of a man who suffered the unthinkable. Writer Mark Cowan also explores the grimly fascinating history of decompression sickness, the science behind what causes the disease, and the stories of the forgotten divers who pushed the limits of physical endurance to help find a solution.

Featuring the work of recognized worldwide experts, this user-friendly text presents the most current scientific information, diagnostic approaches, and management strategies for the care of children with acute and chronic respiratory diseases. A consistent chapter format enables you to rapidly and effortlessly locate the most current protocols on manifestations, etiologies, triggers, approaches to treatment, complications, and preventative strategies. And, a bonus website—new to this edition—features all of the book’s illustrations and extensive reference lists for each chapter in electronic format for your personal use. Includes guidance on differential diagnosis to help you determine which disease or condition your patient may have. Uses extensive color-coded algorithms to facilitate quick diagnosis, management, and treatment decisions. Organizes material to parallel your clinical decision making process. Provides expert guidance on what diagnostic tests to order for each patient—and how to interpret the results. Presents important “take home concepts within each chapter to help you recall clinical pearls. Includes the most need-to-know basic science, focusing on providing clear implications for patient care. Includes a separate website with all of the images from the text and extensive reference lists—downloadable for your personal use. Provides the latest scientific information and diagnostic and management strategies for the care of children with respiratory illnesses. Features a new, functional four-color design to help you identify important information quickly and differentiate between essential and extraneous material. Presents cutting-edge coverage with new information on the biology of, and the influences on, the respiratory system during childhood, as well as the diagnosis and management of both common (ie, wheezing infant, cystic fibrosis, tuberculosis) and less common (ie, SARS, chest tumors, collagen vascular diseases, Familial Mediterranean Fever) conditions.

Dyneins are molecular motors that are involved in various cellular processes, such as cilia and flagella motility, vesicular transport, and mitosis. Since the first edition of this book was published in 2012, there has been a significant breakthrough: the crystal structures of the motor domains of cytoplasmic dynein have been solved and the previously unknown details of this huge and complex molecule have been unveiled. This new edition contains 14 chapters written by researchers in the US, Europe, and Asia, including 3 new chapters that incorporate new fields. The other chapters have also been substantially updated. Compared with the earlier edition, this book focuses more on the motile mechanisms of dynein, especially by biophysical methods such as cryo-EM, X-ray crystallography, and single-molecule nanometry. It is a major handbook for frontline researchers as well as for advanced students studying cell biology, molecular biology, biochemistry, biophysics, and structural biology.