Aunt Jane's Nieces is the title of a juvenile novel published in 1906, and written by L. Frank Baum under the pen name "Edith Van Dyne." Since the book was the first in a series of novels designed for adolescent girls, its title was applied to the entire series of ten books, published between 1906 and 1918. The novel "is genuinely original and interesting. It focuses on three adolescent girls, two of whom combine basic good character with ugly traits not usually found in fiction for young girls. Baum starts with a trite situation that could occasion prosy moralizing and gives it several original twists." The rest of the novels in the series feature travel, adventures, accidents, a kidnapping and rescue, romances, and a marriage for Louise. The final novel, Aunt Jane's Nieces in the Red Cross, was originally published in 1915.

Aunt Jane's nieces go to work campaigning for their cousin who is running for Congress against a powerful incumbent, and solve a mystery along the way.