Like all specialized areas of medicine, that of joint disease informative. The techniques, practical and interpretive, has become surrounded by a practical mystique and are highly reproducible and simple, allowing them to be applied in any laboratory. jargon specific to itself. The number of clinicians working Although we see this volume as being of value to all in the field is large but the number of pathologists small. interested in joint disease it is specifically aimed at It follows that the majority of pathologists are at somewhat laboratory staff wishing to offer a synovial fluid analytical of an immediate disadvantage when discussing and ana service. Like most cytology we believe much of the cell lysing articular problems with their rheumatological and and non-cell identification and quantitation can, and orthopaedic colleagues. should, be undertaken by trained technical staff. The book In the specific area of synovial fluid examination the is therefore aimed primarily at two groups: pathologists difficulties for the pathologist are compounded because who do not specialize in joint disease and technical staff to date there have been no basic texts that detail the who will be generating the data on which interpretation methods, findings and interpretation of the macroscopic will be based. It is therefore both a text book and a bench and microscopic characteristics of the fluid in the common reference manual. arthropathies. In this book we hope to go some way We do not believe our data or methodology represent towards rectifying this omission.

Clinical Atlas of Small Animal Cytology provides an essential guide for interpreting cytologic samples to diagnose small animal patients. Features photographs of diseases with a diagnosis confirmed by pathognomonic cytologic features, histopathology, special stains, microbial culture, or other confirmatory tests Emphasizes characteristic features of each disease and distinguishing features Provides multiple images to differentiate cells from lesions that could look similar Presents more than 500 representative high-quality images

It is hoped that this book may serve two purposes. felt that the resulting increase in size and expense of First it is intended for use at the bench. to help solve the book would not be justified. some of the problems of cell identification which The material was collected over many years and puzzle not only beginners. but even experienced we cannot individually acknowledge the great contri observers in the field of cytological diagnosis. Sec bution made by technical staff of the clinical cytology ondly we have reviewed the most significant previous laboratories who assisted the two authors to prepare publications. particularly those of the past 20 years. and stain the sl ides. Most of the electron micrographs so as to provide a source of reference. were made by or with the assistance of the late Denis Cytological diagnosis should not be isolated from W. Jerrome. and we are also grateful to Dr David histopathology. and many readers will regret the lack Ferguson for further help and advice with these. All of the immunocytochemical stains were done by Dr of cyto-histological correlation in our choice of photographs. Cells centrifuged out of suspension in Anna Ghosh. and Drs David Mason and Kevin Gatter pathological fluids bear very little resemblance to kindly commented on that part of the manuscript. their counterparts in tissue sections.

Clinical Atlas of Small Animal Cytology and Hematology A comprehensive image-based reference to all aspects of small animal cytology and hematology, including sample collection and handling Clinical Atlas of Small Animal Cytology and Hematology, Second Edition is an essential, comprehensive resource for all veterinary professionals preparing and evaluating cytology and blood samples. Featuring hundreds of large, high-quality images, this fully updated new edition provides an even more extensive collection of exceptional photomicrographs, accompanied by detailed descriptions, figure legends and annotations to guide readers through the diagnostic process. The Second Edition adds an extensive new hematology section, new chapters detailing sample acquisition and preparation, and many new diseases across all chapters. Each section provides a detailed description of the microscopic appearance, clinical considerations, and prognosis for each disease, using a bullet point format to promote rapid review for efficient, evidence-based clinical decision making. Clinical Atlas of Small Animal Cytology and Hematology features: More than 750 high-quality cytology and hematology images 6 new chapters, including detailed sections on sample acquisition and the preparation and staining of cytology and hematology slides A comprehensive hematology section including an easy-to-follow blood smear interpretation guide, and detailed chapters describing erythrocytes, leukocytes, platelets and background features Updated cytology sections with new diseases and images in all chapters Easy to use, with superior quality images and detailed yet succinct clinical information, Clinical Atlas of Small Animal Cytology and Hematology is a powerful resource to help improve confidence and skill in the interpretation of cytology and hematology samples, and in turn positively impact patient care and outcomes.

This succinct book guides the trainee through the hurdles of fledgling cytology practice and can also be used throughout the career as an aide memoire by the more experienced. Whilst there are several well established and excellent textbooks on general cytology, these are by and large reference books rather than bench books that can lie beside each individual trainee’s microscope and be resourced continually before and during each case. With numerous illustrations to enthuse the reader and make cytological practice a more enjoyable and educational experience, the book also highlights points of diagnostic difficulty, particularly with regard to the differentiation of neoplastic from non-neoplastic disease. This bench book will be an invaluable reference guide to histo- and cyto-pathology trainees as well as consultants who want a quick refresher/reference point.

Covering both the scientific basis of rheumatology and practical, clinical information for rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast-changing field. Dr. Marc Hochberg and his team of worldwide editors and authors keep you abreast of recent advances in the field— all in a user-friendly, accessible manner. Fully updated from cover to cover, this two-volume text is designed to meet the needs of all practicing and academic rheumatologists as well as arthritis-related health care professionals and scientists interested in rheumatic and musculoskeletal diseases. Covers the epidemiology, pathogenesis, clinical manifestations, therapeutic approach, and management of all major as well as rarely encountered rheumatic and musculoskeletal diseases. Discusses clinical examination, imaging principles, differential diagnosis, established and novel therapies, perioperative evaluation, pain management, basic science, and genetics of rheumatic and musculoskeletal diseases. Uses a consistent, logical, reader-friendly format with templated chapters, concise text, and large-scale, state-of-the-art illustrations for efficient visual reference. Contains new chapters covering pre-clinical disease and how to address these patients, common comorbidities in rheumatoid arthritis; emerging therapies for systemic sclerosis; immune mediated complications of checkpoint inhibitors; the epidemiology of COVID-19 and rheumatic and musculoskeletal diseases, emerging treatments for osteoarthritis, and big data analytics. Provides updates to key topics such as systems biology and its impact on our understanding of the pathogenesis of rheumatic and musculoskeletal diseases, the microbiome in rheumatic musculoskeletal diseases, how to manage chronic pain in the patient with a rheumatic disease, drugs and reproductive health, and emerging therapies for patients with RA, SLE, spondyloarthritis, inflammatory muscle disease, and vasculitis. Shares the knowledge and expertise of numerous new contributing authors, as well as new co-editor Dr. Désirée van der Heijde, who is an expert in psoriatic arthritis, spondyloarthritis, imaging, and clinical epidemiology. Provides access to concise videos depicting the use of ultrasound for diagnosis and treatment. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. If you encounter issues with your eBook please contact Elsevier eBook+ support via [email protected].