This book reflects the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment of musculoskeletal tumor and tumorlike lesions. It presents a wide range of lesions from a multidisciplinary perspective, highlighting pertinent clinical, radiological, and histological correlations. Treatment is briefly reported for each entity. In addition, the more recent biomolecular findings of use for diagnosis, prognosis, and treatment are carefully analyzed. The Rizzoli case archive spans more than a century, the first treated case dating back to 28 September 1900, and contains the original material – clinical charts, imaging, paraffin blocks, and histological slides – of more than 40,000 cases, including about 29,000 bone lesions and 11,000 soft tissue lesions. This book reports the most relevant entities and reflects the improvements in knowledge of musculoskeletal tumors as presented during the yearly international course held at the Rizzoli Institute.​

"This unique encyclopedic guide takes the same approach you apply in clinical practice. It features fully illustrated differential diagnosis tables organized according to MRI findings and the locations of tumors. An in-depth reference section provides information on each lesion. In addition, almost 3000 high-quality images make this practical text an invaluable tool in the diagnosis of common and rare tumors and other disorders of the musculoskeletal system." "Features: 20 differential diagnosis tables based on anatomic locations of lesions rather than disease; fully illustrated reference chapters containing concise, detailed information for each lesion - from relative frequency and age rangers to MRI findings, treatment, and prognosis; over 2900 state-of-the-art illustrations covering the wide range of imaging features for various lesions; an exceptional level of detail, helping you to differentiate between diseases and conditions that have similar appearances; and extensive cross-referencing to further up-to-the minute resources."--BOOK JACKET.

This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.

This volume presents both the radiologist's and the pathologist's approach to differential diagnosis of musculoskeletal tumors and tumor-like lesions and details the radiologic and histopathologic features helpful in confirming a diagnosis. The book is illustrated with over 1,200 radiographs, CT and MR images, full-color photomicrographs, and schematic drawings. Tables list important diagnostic features, and schematic drawings summarize both radiologic and pathologic differential diagnoses. This edition includes state-of-the-art information on PET, thin-section CT, 3-D CT, MRI, enzyme histochemistry, immunohistochemistry, flow cytometry, cytogenetics, and molecular cytogenetics. The new co-author, Gernot Jundt, was instrumental in revising the WHO classification of musculoskeletal lesions. Illustrations have been updated, and improved captions begin with the diagnosis.

Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.

An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.