Aspects of Nuclear Structure and Function deals with various aspects of nuclear structure and function and covers topics ranging from the ultrastructure of the female gamete to the structure, biochemistry, and functions of the nuclear envelope. Banding patterns in chromosomes, histones and nonhistone proteins, and the transfer of genetic information in polytene cells are also discussed. This book is comprised of six chapters and begins by presenting a comparative view of some aspects of the ultrastructure of the vegetative (growth) aspects of oogenesis, with emphasis on microtubules, intercellular bridges of differentiating oocytes, and vitellogenesis as well as accessory structures of the egg envelope. The following chapters explore the structure, biochemistry, and functions of the nuclear envelope; banding patterns in chromosomes; chromosomal proteins (histones and nonhistone proteins); transfer of genetic information in polytene cells; and the intracellular biology of DNA polymerases in eukaryotic cells, their association with the nucleus, and how this association changes during the mitotic cell cycle. The relationship between eukaryotic DNA polymerases and DNA replication is also examined. This monograph should be a valuable resource for biochemists.

The nucleus guides the life processes of the cell by directing cellular reproduction, differentiation during development, and metabolism. The study of the structure and function of the nucleus along with its genetic material serves as the foundation for the science of genetics. Principles of Nuclear Structure and Function provides a comprehensive overview of the cell nucleus by illustrating the connection between function and the architecture of the nucleus. Richly illustrated throughout, each chapter includes an overview, detailed examples, summary points, references, and callout boxes highlighting methods and cutting-edge technology. The appendix provides a useful list of related Web sites. Some of the subjects reviewed within Principles of Nuclear Structure and Function include: * Nuclear structure, replication, damage, and repair * Regulation of gene expression * The cell cycle * Meiosis and recombination This timely volume presents functional studies within their proper structural context and is an informative profile of the cell and molecular biology in nuclei and chromatin. For those studying cell biology, along with molecular and cell biologists, geneticists, and reproductive biologists, Principles of Nuclear Structure and Function is a definitive resource. Visit www.wiley.com/cook for supplementary information, including additional Web resources, downloadable figures, and discussion questions.

This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols

'The field has expanded in so many directions, in connection with the increase in accessible energy, angular momentum, and nuclear species, and the new phenomena, which have been revealed, have stimulated conceptual developments concerning the significant degrees of freedom and their interplay in nuclear dynamics ... it would be impossible for us to provide an assessment of this vastly expanded subject with anything like the degree of comprehensiveness aimed at in the original text. At the same time, this text continues to describe the basis for the understanding of nuclear structures as we see it today ...'foreword from the new prefaceAfter many years, this classic two-volume treatise is now available again in an unabridged reprint. These volumes present the basic features of nuclear structure in terms of an integration of collective and independent particle aspects and remain a foundation for current efforts in the field. Central to the book's value is an approach that recognizes the many connections between concepts of nuclear physics and those of other many-body systems, and that deals boldly with the interplay between theory and experiment. Aside from the main text, which provides a systematic exposition of the subject, there are sections labeled ';Illustrative Examples';, which present detailed analyses of experimental results and the manner in which they illuminate the concepts developed in the text. Many useful appendices on general theoretical tools are also included, covering topics such as angular momentum algebra, symmetry problems, statistical description of level densities, and theory of nuclear reactions and decays.

Nuclear Structure covers material usually discussed in courses about nuclear structure. The presentation, although recommends and not necessarily requires the reader to have some knowledge of introductory nuclear physics at an elementary or undergraduate level, requires a good knowledge of the elements of quantum mechanics, including an introduction to Dirac theory. The text covers topics such as nucleon-nucleon forces, the boson-exchange model, high-energy electron scattering, and the single particle shell model. Also covered are topics such as single-particle potentials, spin-orbit interactions, the individual-particle model, states of different nuclei, electromagnetic interactions with nuclei, and beta-decay. The book is recommended for nuclear physics students who have background knowledge on nuclear structure and would like to know more about the topic.

Dramatic progress has been made in all branches of physics since the National Research Council's 1986 decadal survey of the field. The Physics in a New Era series explores these advances and looks ahead to future goals. The series includes assessments of the major subfields and reports on several smaller subfields, and preparation has begun on an overview volume on the unity of physics, its relationships to other fields, and its contributions to national needs. Nuclear Physics is the latest volume of the series. The book describes current activity in understanding nuclear structure and symmetries, the behavior of matter at extreme densities, the role of nuclear physics in astrophysics and cosmology, and the instrumentation and facilities used by the field. It makes recommendations on the resources needed for experimental and theoretical advances in the coming decade.

Invited Papers presented at the 4th International Conference on Clustering Aspects of Nuclear Structure and Nuclear Reactions, Chester, 23-27 July, 1984