Nunn's Applied Respiratory Physiology

A modern quantitative study of lung mechanics, relating mathematical modeling and engineering principles to lung function, structure, mechanics, and disease.

This is a text for anaesthetists, physiologists and anyone seeking information about the basic principles and applications of lung function. This edition has been revised to include new scientific findings.

The close correlations between anatomo-functional data and clinical aspects are substantiated by the study and interpretation of the data of respiratory mechan ics. This field has developed to such an extent that, today, it is hard to single out one researcher who is an expert of the whole sector, whereas super experts can be found among scholars who, thanks to their studies and continuous comparisons, have contributed to the widening of knowledge and the development of that part of research which correlates some basic disciplines with clinical medicine. This notion is of paramount importance. Indeed, it has to be regarded as a starting point requiring a more precise definition. The analysis of data concern ing ventilation parameters is based on the use of mathematical models that are necessary to simplify the complexity of the various clinical situations. For a cor rect application and interpretation of data, the most recent technological acquisi tions in terms of ventilatory support require to be used as a function of simple mathematical models for the study, control and evolution of the lung diseases that concern the ICU. Thus, the need has arisen to compare the experience acquired in the field of applied physiology and in the clinical sector.

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Medical Ventilator System Basics: A clinical guide is a user-friendly guide to the basic principles and the technical aspects of mechanical ventilation and modern complex ventilator systems. Designed to be used at the bed side by busy clinicians, this book demystifies the internal workings of ventilators so they can be used with confidence for day-to-day needs, for advanced ventilation, as well as for patients who are difficult to wean off the ventilator. Using clear language, the author guides the reader from pneumatic principles to the anatomy and physiology of respiration. Split into 16 easy to read chapters, this guide discusses the system components such as the ventilator, breathing circuit, and humidifier, and considers the major ventilator functions, including the control parameters and alarms. Including over 200 full-colour illustrations and practical troubleshooting information you can rely on, regardless of ventilator models or brands, this guide is an invaluable quick-reference resource for both experienced and inexperienced users.

Nunn's Applied Respiratory Physiology, Seventh Edition covers all aspects of respiratory physiology in health, disease, and altered conditions and environments, from basic science to clinical applications. Includes functional anatomy, mechanics, control of breathing, ventilation, circulation, ventilation-perfusion matching, diffusion, carbon dioxide and oxygen, and non-respiratory functions of the lung. Discusses the effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia on respiratory physiology. Explores specific clinical disorders such as ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury, as well as the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation. Chapter on Parenchymal Lung Disease has been specifically expanded to include the physiology and pathology of the pleural space and lung cancer. Contains a new chapter on Pulmonary Surgery, covering a wide range of surgical interventions from bronchoscopy to lung resection. Includes almost 500 new references to the literature. The result is an invaluable source for those preparing for examinations in anaesthesia and intensive care, as well as an essential purchase for practitioners who want quick reference to current knowledge. Describes respiration in health and disease and in normal and abnormal situations, to help readers manage all conditions they see in their practices. Examines the respiratory effects of exercise, sleep, smoking, anaesthesia, drowning, anaemia, pregnancy, and other events as well as environmental factors such as altitude, flying, high pressure, closed environments, and air pollution on respiration. Maintains the clarity of style and single-author approach of previous editions through the close collaboration of Andrew Lumb and John Nunn. Makes difficult concepts easy to understand and apply with nearly 300 illustrations. A new chapter on the History of Respiratory Physiology. More coverage of pathophysiology and even more applications of respiratory physiology to clinical practice. A more consistent organization, a revised page design that aids readability, and an art program featuring new and newly redrawn illustrations.