The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. In this second volume some of the most renowned experts in the field offer detailed reviews on measurement techniques and physiological processes of crucial importance in intensive care medicine. Throughout, a key aim is to help overcome the fundamental unevenness in clinicians’ understanding of applied physiology, which can lead to suboptimal treatment decisions. Applied Physiology in Intensive Care has been written by some of the most renowned experts in the field and provides an up-to-date compendium of practical bedside knowledge essential to the effective delivery of acute care medicine. It will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.

Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primarily on physiologic principles in determining the best treatments and response to therapy. However, the physiologic foundation present in practicing physicians is uneven and occasionally supported more by habit or prior training than science. A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o cia t ed r e vie w a r tic les o v er t h e s a m e in t er val t ha t a ls o addr ess e d t hes e cen tral issues.

The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. This first volume comprises three elements -- "physiological notes," “technical notes,” and seminal studies. The physiological notes concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The technical notes then succinctly explain some of the basics of “how to” in this technology-centered field of critical care medicine. Finally, a number of seminal studies are provided on diverse topics in intensive care. Applied Physiology in Intensive Care, written by some of the most renowned experts in the field, is an up-to-date compendium of practical bedside knowledge that will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.

A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.

Nunn's Applied Respiratory Physiology

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers.

Nunn's Applied Respiratory Physiology, Seventh Edition covers all aspects of respiratory physiology in health, disease, and altered conditions and environments, from basic science to clinical applications. Includes functional anatomy, mechanics, control of breathing, ventilation, circulation, ventilation-perfusion matching, diffusion, carbon dioxide and oxygen, and non-respiratory functions of the lung. Discusses the effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia on respiratory physiology. Explores specific clinical disorders such as ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury, as well as the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation. Chapter on Parenchymal Lung Disease has been specifically expanded to include the physiology and pathology of the pleural space and lung cancer. Contains a new chapter on Pulmonary Surgery, covering a wide range of surgical interventions from bronchoscopy to lung resection. Includes almost 500 new references to the literature. The result is an invaluable source for those preparing for examinations in anaesthesia and intensive care, as well as an essential purchase for practitioners who want quick reference to current knowledge. Describes respiration in health and disease and in normal and abnormal situations, to help readers manage all conditions they see in their practices. Examines the respiratory effects of exercise, sleep, smoking, anaesthesia, drowning, anaemia, pregnancy, and other events as well as environmental factors such as altitude, flying, high pressure, closed environments, and air pollution on respiration. Maintains the clarity of style and single-author approach of previous editions through the close collaboration of Andrew Lumb and John Nunn. Makes difficult concepts easy to understand and apply with nearly 300 illustrations. A new chapter on the History of Respiratory Physiology. More coverage of pathophysiology and even more applications of respiratory physiology to clinical practice. A more consistent organization, a revised page design that aids readability, and an art program featuring new and newly redrawn illustrations.