Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing

Neuro-Otology: a volume in the Handbook of Clinical Neurology series, provides a comprehensive translational reference on the disorders of the peripheral and central vestibular system. The volume is aimed at serving clinical neurologists who wish to know the most current established information related to dizziness and disequilibrium from a clinical, yet scholarly, perspective. This handbook sets the new standard for comprehensive multi-authored textbooks in the field of neuro-otology. The volume is divided into three sections, including basic aspects, diagnostic and therapeutic management, and neuro-otologic disorders. Internationally acclaimed chapter authors represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. The Basic Aspects section is brief and covers the material in sufficient depth necessary for understanding later translational and clinical material. The Diagnostic and Therapeutic Management section covers all of the essential topics in the evaluation and treatment of patients with dizziness and disequilibrium. The section on Neuro-otologic Disorders is the largest portion of the volume and addresses every major diagnostic category in the field. - Synthesizes widely dispersed information on the anatomy and physiology of neuro-otologic conditions into one comprehensive resource - Features input from renowned international authors in basic science, otology, and neuroscience - Presents the latest assessment of the techniques needed to diagnose and treat patients with dizziness, vertigo, and imbalance - Provides the reader with an updated, in-depth review of the clinically relevant science and the clinical approach to those disorders of the peripheral and central vestibular system

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Experts describe current perspectives and experimental approaches to understanding the neural bases of creativity. This volume offers a comprehensive overview of the latest neuroscientific approaches to the scientific study of creativity. In chapters that progress logically from neurobiological fundamentals to systems neuroscience and neuroimaging, leading scholars describe the latest theoretical, genetic, structural, clinical, functional, and applied research on the neural bases of creativity. The treatment is both broad and in depth, offering a range of neuroscientific perspectives with detailed coverage by experts in each area. The contributors discuss such issues as the heritability of creativity; creativity in patients with brain damage, neurodegenerative conditions, and mental illness; clinical interventions and the relationship between psychopathology and creativity; neuroimaging studies of intelligence and creativity; the neuroscientific basis of creativity-enhancing methodologies; and the information-processing challenges of viewing visual art. Contributors Baptiste Barbot, Mathias Benedek, David Q. Beversdorf, Aaron P. Blaisdell, Margaret A. Boden, Dorret I. Boomsma, Adam S. Bristol, Shelley Carson, Marleen H. M. de Moor, Andreas Fink, Liane Gabora, Dennis Garlick, Elena L. Grigorenko, Richard J. Haier, Rex E. Jung, James C. Kaufman, Helmut Leder, Kenneth J. Leising, Bruce L. Miller, Apara Ranjan, Mark P. Roeling, W. David Stahlman, Mei Tan, Pablo P. L. Tinio, Oshin Vartanian, Indre V. Viskontas, Dahlia W. Zaidel