This package includes a three-hole punched, loose-leaf edition of ISBN 9781118393680 and a registration code for the WileyPLUS course associated with the text. Before you purchase, check with your instructor or review your course syllabus to ensure that your instructor requires WileyPLUS. For customer technical support, please visit http://www.wileyplus.com/support. WileyPLUS registration cards are only included with new products. Used and rental products may not include WileyPLUS registration cards. Applied Calculus is praised for the creative and varied conceptual and modeling problems which motivate and challenge students. The 5th Edition of this market leading text exhibits the same strengths from earlier editions including the "Rule of Four," an emphasis on concepts and modeling, exposition that students can read and understand and a flexible approach to technology. New case studies on medicine by David E. Sloane, M.D. are included as well as updated data and fresh applications throughout the book.