Applications of Genomics and Proteomics for Analysis of Bacterial Biological Warfare Agents

Applications of Genomics and Proteomics for Analysis of Bacterial Biological Warfare Agents
Title Applications of Genomics and Proteomics for Analysis of Bacterial Biological Warfare Agents PDF eBook
Author Vito G. DelVecchio
Publisher IOS Press
Pages 254
Release 2003
Genre Bacterial diseases
ISBN 9781586033439

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Toxicogenomics and Proteomics

Toxicogenomics and Proteomics
Title Toxicogenomics and Proteomics PDF eBook
Author James J. Valdes
Publisher IOS Press
Pages 220
Release 2004
Genre Medical
ISBN 9781586034023

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Annotation The field of toxicology has developed a well-characterized set of techniques to assess the behavioral and histopathological consequences of exposure to environmental insults using a number of animal models. These techniques are suitable for determining crude endpoints of exposure such as death, but are not optimal for assessing the more subtle effects of very low level or multi-agent chemical exposures, nor do they offer mechanistic explanations at the molecular level. This book is designed to have a mix of chapters devoted to classical toxicology followed by those focused more on the emerging techniques of toxicogenomics and proteomics. In this way, the relevance of new technologies such as gene arrays to classical toxicologic problems is made evident. Finally, because the worst of the world's toxicology problems reside in developing nations while the latest technical developments are occurring in the industrial nations, we sought to provide a balance of both scientific and geographical perspectives from researchers engaged in toxicology and public health research.

Emerging Biological Threat

Emerging Biological Threat
Title Emerging Biological Threat PDF eBook
Author Akbar S. Khan
Publisher IOS Press
Pages 192
Release 2005
Genre Biological weapons
ISBN 158603555X

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Historical Dictionary of Nuclear, Biological, and Chemical Warfare

Historical Dictionary of Nuclear, Biological, and Chemical Warfare
Title Historical Dictionary of Nuclear, Biological, and Chemical Warfare PDF eBook
Author Benjamin C. Garrett
Publisher Rowman & Littlefield
Pages 411
Release 2017-08-25
Genre History
ISBN 1538106841

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The history of biological weapons (BW), chemical weapons (CW), and nuclear weapons is complicated. It can be disturbing, tragic, and occasionally encouraging. It is rarely amusing, although the names selected for certain weapons suggest a casualness toward the consequences of their use: Atomic Annie, Blue Peacock, Dew of Death, Fat Man, Flying cow, George, Gilda, Helen of Bikini, Hurricane, Katie, Little Boy, Lulu, Mike, Red Beard, Sewer Pipe, Squirt. Use of BW and CW in warfare has produced mixed results in terms of effecting the outcome of a battle or campaign; despite this mixed record, both weapon types have attracted intense interest and strong advocacy for further use. The sole experience with use of nuclear weapons in warfare is viewed as hastening surrender by Japan, created competition among nations to develop more such weapons, and influenced efforts to ban any use or even stockpiling of such weapons. Each of these three weapon types has its own peculiar history, as recounted in this dictionary. This second edition of Historical Dictionary of Nuclear, Biological and Chemical Warfare contains a chronology, an introduction, and an extensive bibliography. The dictionary section has over 700 cross-referenced entries onterms related to NBC warfare, ranging from basic descriptions of substances used to details on incidents and episodes where NBC weapons were used, historical events, persons important to NBC warfare, countries where such weapons have been developed or used, and international treaties and treaty-related organizations.

The A to Z of Nuclear, Biological and Chemical Warfare

The A to Z of Nuclear, Biological and Chemical Warfare
Title The A to Z of Nuclear, Biological and Chemical Warfare PDF eBook
Author Benjamin C. Garrett
Publisher Scarecrow Press
Pages 302
Release 2009-09-16
Genre History
ISBN 0810870401

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Human experience with nuclear, biological, and chemical (NBC) warfare has been limited, especially in comparison to conventional forms of warfare. Our experience with nuclear warfare is confined to a period of less than one week during the end of World War II, when the United States successfully used two nuclear weapons against targets in Japan. The course of biological warfare and modern use of biological weapons are difficult to track owing to the difficulty of differentiating deliberate use from natural outbreaks. However, the keen potential of biological weapons in acts of terror was shown in the mass disruption caused in the fall 2001 experience in the U.S. with the release of anthrax through the American postal system. Chemical weapons have been used in a handful of conflicts since their introduction to modern warfare during World War I, most recently during the Iran-Iraq War during the 1980s. Despite this limited experience, NBC warfare continues to exert a certain fascination among states. The A to Z of Nuclear, Biological, and Chemical Warfare covers the development and use of NBC weapons as well as efforts to limit or control the use of these weapons through a chronology, a bibliography, an introductory essay, and dictionary entries. Over 500 cross-referenced dictionary entries provide a unique selection of terms related to NBC warfare, ranging from basic descriptions of substances used in NBC warfare to details on incidents and episodes where NBC weapons were used. Entries are structured around historical events, persons important to NBC warfare, countries where such weapons have been developed or used, and international treaties and treaty-related organizations.

Brucella:Molecular & Cell Biol

Brucella:Molecular & Cell Biol
Title Brucella:Molecular & Cell Biol PDF eBook
Author Ignacio Lopez-Goni
Publisher Taylor & Francis
Pages 447
Release 2005-11-08
Genre Science
ISBN 1136800077

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The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.

Microbial Forensics

Microbial Forensics
Title Microbial Forensics PDF eBook
Author Bruce Budowle
Publisher Academic Press
Pages 753
Release 2010-10-27
Genre Science
ISBN 0123820073

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Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease