In this issue of Interventional Cardiology Clinics, guest editor Dr. Luis Ortega Paz brings his considerable expertise to the topic of Antiplatelet and Anticoagulation Therapy in Cardiovascular and Pulmonary Embolism Transcatheter Interventions. Top experts in the field discuss regulation of platelet activation and coagulation; genetic determinants of P2Y12 inhibitors and clinical implications; switching P2Y12 receptor inhibiting therapies; high bleeding risk in patients undergoing coronary and structural heart interventions; and much more. - Contains 13 relevant, practice-oriented topics including antithrombotic therapy in atrial fibrillation patients undergoing coronary stenting; antithrombotic therapy in patients undergoing transcatheter aortic valve replacement; antithrombotic therapy in patients undergoing peripheral artery interventions; antiplatelet therapy in women; and more. - Provides in-depth clinical reviews on antiplatelet and anticoagulation therapy in cardiovascular and pulmonary embolism transcatheter interventions, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Interventional Cardiology Clinics, edited by Drs. Dominick Angiolillo and Matthew Price, will focus on Antiplatelet and Anticoagulation Therapy in PCI. The topics covered in this volume will span across pretreatment with antiplatelet agents; optimal duration of antiplatelet therapy after PCI; Cangrelor and its role in percutaneous coronary intervention; Ticagrelor and its effects beyond the P2Y12 receptor; dyspnea and Reversibly-binding P2Y12 antagonists; PAR receptor inhibition post-PCI; switching P2Y12 receptor inhibiting therapies; antiplatelet and antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting; antithrombotic therapy to reduce ischemic events in ACS patients undergoing PCI; and the current role of platelet function testing in PCI and CABG, among other topics.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Interventional Cardiology Clinics, guest edited by Dr. Ravi S. Hira, will cover the latest updates regarding State of the Art in STEMI Care. This issue is one of four selected each year by the series Editor-in-Chief, Dr. Marvin H. Eng. Topics discussed in this issue will include: Regional systems of care, Prehospital evaluation, ED management, transfers and management of inpatient STEMI, Antiplatelet therapy - discuss ADP antagonists, IIB/IIIA use, Anticoagulant therapy, Aspiration thrombectomy, Diagnosis and management of late presentation STEMI and complications, Use of fibrinolytic therapy in patients with STEMI and more.

This issue of Interventional Cardiology Clinics, guest edited by Editor-in-Chief Matthew J. Price, will focus on Key Trials of the Decade. Trials discussed in this issue will include: Physiology over Angiography to determine lesion severity: The FAME trials; Percutaneous Coronary Intervention or surgery for multivessel disease: The SYNTAX trial at 10 years; Percutaneous Coronary Intervention or surgery for unprotected left main disease: The EXCEL trial at 5 years; Complete or Incomplete Revascularization for ST-Elevation Myocardial Infarction: the PRAMI trial and beyond; Abbreviated Dual Antiplatelet Therapy after PCI in High Bleeding Risk Patients: LEADERS-FREE and ONYX ONE; Transcatheter treatment of functional mitral regurgitation in patients with heart failure: The COAPT trial; Manual thrombectomy in Primary Percutaneous Coronary Intervention: Lessons learned from TOTAL; Paradigm shifts in the treatment of aortic stenosis: The PARTNER Trials experience; COURAGE and ORBITA in context: PCI for chronic stable CAD; SIMPLICITY to RADIANCE: Interpreting the past and mapping the future of renal denervation; From WOEST to AUGUSTUS: Dual Therapy after PCI; The ISCHEMIA Trial: Background, Design, Outcomes and Clinical Interpretation.

Clinical application of antithrombotic therapy in both arterial disease (acute coronary syndromes, acute MI, peripheral arterial disease, valvular heart disease, atrial fibrillation) and venous disease, (venous thromboembolic disease and pulmonary embolism). Results of major clinical trials and their implications for clinical practice.

This issue of Interventional Cardiology Clinics covers bypass graft lesions and thrombectomy. Expert authors review the most current information available about saphenous vein grafts, including distal embolic protection devices, drug eluting stents vs bare metal stents, management of complications, optimal stenting, and more. Adjunctive pharmacotherapy for thrombotic coronary lesions and thrombectomy devices in coronary intervention are also discussed. Keep up-to-the-minute with the latest developments in this important aspect of interventional cardiology practice.