Lack of clean water, inadequate sanitation, and insufficient infection prevention and control promote the spread of parasites. The discovery of antiparasitic drugs was considered a milestone in the veterinary and medical sciences, but their use has subsequently become limited due to the emergence of resistance. While plenty of attention has been given in human and animal health communities to the global threat of antimicrobial drug resistance, specific antiparasitic advice is less available. This book provides an in-depth view of the issue for parasitologists, pharmacologists and veterinary scientists. Specifically discussing antiparasitic drug resistance mechanisms and factors responsible for the problem.

The first book to offer practical guidelines on the prudent andrational use of antimicrobials in animals. Drawing onmultidisciplinary expertise to offer independent scientific adviceon a controversial area that is crucial to both human health andanimal welfare. The earlier general chapters cover issues such ashuman health risks and the problems of resistance to antimicrobialdrugs. The later specific chapters are dedicated to particulargroups of animals. Has an emphasis on preserving the efficacy of antimicrobialdrugs that are clinically important in human medicine Covers both companion animals and food animals, includingaquaculture Suitable for veterinary practitioners working in small andlarge animal medicine, aquaculture and animal production, as wellas veterinary students, academics and researchers. It will also beof interest to those more generally involved in veterinary publichealth and antimicrobial resistance.

With 21 expert contributors, this third edition is revised and expanded. Its revision is due in part to the crisis of antibiotic resistance in human medicine and to extensive re-examination of the practice of using feed antibiotics as growth promoters and disease prophylactics in animals. Well-organized and easy to read, this comprehensive summary will be an invaluable guide to anyone making therapeutic decisions in the veterinary profession.

Antiparasitic drugs (ATH) are important tools widely used to maintain animal welfare. As parasites impart a great impact on animal health, these drugs are often essential for the expression of the full genetic potential of production. However, despite the initial success, after years of massive use of anthelminthic drugs , the increase in prevalence of resistant nematodes became a major problem. Anthelmintics are commonly used to treat parasitic worm infections not only in animals, but humans as well. Resistance to anthelmintics is thought to be present in several helminth species, yet it remains poorly studied. This books discusses topics such as the clinical pharmacology of anthelmintics; the uses in human and veterinary medicine; animal resistance to ATH; and the efficacy of Neem and Pawpaw products against Oesophahostomum spp infection in pigs.

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Antiparasitic drugs (ATH) are important tools widely used to maintain animal welfare. As parasites impart a great impact on animal health, these drugs are often essential for the expression of the full genetic potential of production. However, despite the initial success, after years of massive use of anthelminthic drugs, the increase in prevalence of resistant nematodes became a major problem. Anthelmintics are commonly used to treat parasitic worm infections not only in animals, but humans as well. Resistance to anthelmintics is thought to be present in several helminth species, yet it remains poorly studied. This books discusses topics such as the clinical pharmacology of anthelmintics; the uses in human and veterinary medicine; animal resistance to ATH; and the efficacy of Neem and Pawpaw products against Oesophahostomum spp infection in pigs.