Identifies household poisoning risks, describes the symptoms of common poisons, and lists over six hundred poisons and their treatment

Self-help books don't seem to work. Few of the many advantages of modern life seem capable of lifting our collective mood. Wealth—even if you can get it—doesn't necessarily lead to happiness. Romance, family life, and work often bring as much stress as joy. We can't even agree on what "happiness" means. So are we engaged in a futile pursuit? Or are we just going about it the wrong way? Looking both east and west, in bulletins from the past and from far afield, Oliver Burkeman introduces us to an unusual group of people who share a single, surprising way of thinking about life. Whether experimental psychologists, terrorism experts, Buddhists, hardheaded business consultants, Greek philosophers, or modern-day gurus, they argue that in our personal lives, and in society at large, it's our constant effort to be happy that is making us miserable. And that there is an alternative path to happiness and success that involves embracing failure, pessimism, insecurity, and uncertainty—the very things we spend our lives trying to avoid. Thought-provoking, counterintuitive, and ultimately uplifting, The Antidote is the intelligent person's guide to understanding the much-misunderstood idea of happiness.

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.

Antidotes provides up-to-date information on the development and clinical use of antidotes, their proposed mechanism of action, toxicity, availability and practical aspects of their clinical use. The antidotes discussed are primarily those either in current use, or under consideration or development. Some other compounds of mainly historical intere

Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals. - Details recent advances in the discovery of natural antidotes from medicinal plants and phytochemicals - Includes advances in the discovery of antidotes to drug intoxications and overdoses - Describes modern screening assays for toxins and drug intoxications - Features information on recent advances in toxicology

Most of us expect to meander through the motions of love, marriage and (textbook) baby in the carriage, but once in a while life has something a little more special in store. Special is an uplifting, candid companion for those in the early stages of navigating a child’s disability, offering honest, reassuring and relatable insight into a largely unknown (and so, initially terrifying) part of our world. It features antidotes to the obsessions at the forefront of a newly minted special-needs parent’s mind: Why has this happened to me? Will I ever stop comparing my child to typical children? How will my relationship survive? Will I be able to work again? Should I have another baby? And the big one: What will my future look like? Inspired by the author’s own crash-landing into special-needs parenthood, and shaped by her conversations with parents of children with wide-ranging disabilities, alongside specialists, psychologists and researchers, Special shares stories, guidance and simple coping strategies to soothe and surprise anyone whose life has taken an unexpected turn.