Modern brain imaging is revolutionizing the study of brain function in health and disease. However, few realize that its origins began in the nineteenth century with Dr. Angelo Mosso's pioneering experiments. A foremost Italian physiologist and scientist, Angelo Mosso studied several patients brought to him with head injuries that exposed their live brains to direct, long-term observation. He took advantage of these rare opportunities to document, for the first time, changes in cerebral blood flow in response to different stimuli, behaviors, and emotions, the very same changes that are now the basis for the measurements underlying modern functional brain imaging. Mosso was widely recognized by his contemporaries for his highly original studies, published both in Italian in 1878 and in German in 1881. Yet there has never been a translation through which this groundbreaking work could be appreciated by the English-speaking world. Indeed, Angelo Mosso's sophisticated experiments were to neuroscience what surgeon William Beaumont's in vivo observations were to gastric physiology fifty years earlier. This unique monograph establishes Mosso's rightful role as the pioneer of brain imaging. Through it, the modern reader, whether expert neuroscientist or interested student, can gain a new perspective on the author's remarkable insights: how behaviors as subtle as thinking about a subject or feeling an emotion produce the changes in pulsations of the brain that he observed and recorded for posterity. Special features of this volume include first a brief summary of Mosso's life. Two pioneers of modern brain imaging, Marcus E. Raichle (winner of the Kavli Prize for Neuroscience) and Gordon M. Shepherd (Yale University Professor of Neurobiology) then review Mosso's work and provide extensive commentary to explain its relevance to modern brain science. The authors not only emphasize Mosso's pioneering role in brain imaging, but also his fundamental contribution to the rise of cognitive neuroscience. The English translation (by historian of medicine Christiane Nockels Fabbri) follows, together with all of the plates and illustrations of the original volume. The result is a classic of neuroscience, now available for wide appreciation by neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.

The pioneer in studies of changes in brain flow that underlie modern brain imaging was Angelo Mosso. This volume provides an English translation of his historic 1881 volume, together with a rich commentary by two leaders of modern brain imaging, Marcus Raichle and Gordon M. Shepherd. The text offers unique insights into the origins of brain imaging and also the rise of modern cognitive neuroscience.

The pioneer in studies of changes in brain flow that underlie modern brain imaging was Angelo Mosso. This volume provides for the first time an English translation of his historic 1881 volume, together with a rich commentary by two leaders of modern brain imaging, Marcus Raichle and Gordon M. Shepherd. The volume offers unique insights into the origins of brain imaging and also the rise of modern cognitive neuroscience. It will be of interest to neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.

The "sequel" to "Brain Mapping: The Methods", covers the utlization of methods for the study of brain structure and function. Organized by systems, it presents information on the normal as well as the diseased brain. It integrates the various methodologies with appropriate usage.

Written by respected academics in neuropsychology, this sixth edition guides students on a comprehensive journey of discovery through the realm of contemporary human neuropsychology. The book has a clinical focus throughout.

Mobile Brain–Body Imaging and the Neuroscience of Art, Innovation and Creativity is a trans-disciplinary, collective, multimedia collaboration that critically uncovers the challenges and opportunities for transformational and innovative research and performance at the nexus of art, science and engineering. This book addresses a set of universal and timeless questions with a profound impact on the human condition: How do the creative arts and aesthetic experiences engage the brain and mind and promote innovation? How do arts–science collaborations employ aesthetics as a means of problem-solving and thereby create meaning? How can the creative arts and neuroscience advance understanding of individuality and social cognition, improve health and promote life-long learning? How are neurotechnologies changing science and artistic expression? How are the arts and citizen science innovating neuroscience studies, informal learning and outreach in the public sphere? Emerging from the 2016 and 2017 International Conferences on Mobile Brain–Body Imaging and the Neuroscience of Art, Innovation and Creativity held in Cancun, Mexico and Valencia, Spain to explore these topics, this book intertwines disciplines and investigates not only their individual products—art and data—but also something more substantive and unique; the international pool of contributors reveals something larger about humanity by revealing the state of the art in collaboration between arts and sciences and providing an investigational roadmap projected from recent advances. Mobile Brain–Body Imaging and the Neuroscience of Art, Innovation and Creativity is written for academic researchers, professionals working in industrial and clinical centers, independent researchers and artists from the performing arts, and other readers interested in understanding emergent innovations at the nexus of art, science, engineering, medicine and the humanities. The book contains language, design features (illustrations, diagrams) to develop a conversational bridge between the disciplines involved supplemented by access to video, artistic presentations and the results of a hackathon from the MoBI conferences.

An accessible introduction to the history, fundamental concepts, challenges, and controversies of the fMRI by one of the pioneers in the field. The discovery of functional MRI (fMRI) methodology in 1991 was a breakthrough in neuroscience research. This non-invasive, relatively high-speed, and high sensitivity method of mapping human brain activity enabled observation of subtle localized changes in blood flow associated with brain activity. Thousands of scientists around the world have not only embraced fMRI as a new and powerful method that complemented their ongoing studies but have also gone on to redirect their research around this revolutionary technique. This volume in the MIT Press Essential Knowledge series offers an accessible introduction to the history, fundamental concepts, challenges, and controversies of fMRI, written by one of the pioneers in the field. Peter Bandettini covers the essentials of fMRI, providing insight and perspective from his nearly three decades of research. He describes other brain imaging and assessment methods; the sources of fMRI contrasts; the basic methodology, from hardware to pulse sequences; brain activation experiment design strategies; and data and image processing. A unique, standalone chapter addresses major controversies in the field, outlining twenty-six challenges that have helped shape fMRI research. Finally, Bandettini lays out the four essential pillars of fMRI: technology, methodology, interpretation, and applications. The book can serve as a guide for the curious nonexpert and a reference for both veteran and novice fMRI scientists.