Molecular biotechnology continues to triumph, as this textbook testifies - edited by one of the academic pioneers in the field and written by experienced professionals. This completely revised second edition covers the entire spectrum, from the fundamentals of molecular and cell biology, via an overview of standard methods and technologies, the application of the various "-omics", and the development of novel drug targets, right up to the significance of system biology in biotechnology. The whole is rounded off by an introduction to industrial biotechnology as well as chapters on company foundation, patent law and marketing. The new edition features: - Large format and full color throughout - Proven structure according to basics, methods, main topics and economic perspectives - New sections on system biology, RNA interference, microscopic techniques, high throughput sequencing, laser applications, biocatalysis, current biomedical applications and drug approval - Optimized teaching with learning targets, a glossary containing around 800 entries, over 500 important abbreviations and further reading. The only resource for those who are seriously interested in the topic. Bonus material available online free of charge: www.wiley-vch.de/home/molecbiotech

On 800 pages this textbook provides students and professionals in life sciences, pharmacy and biochemistry with a very detailed introduction to molecular and cell biology, including standard techniques, key topics, and biotechnology in industry.

MOLECULAR BIOTECHNOLOGY Therapeutic Applications and Strategies SUNIL MAULIK and SALIL D. PATEL Recombinant DNA technology, or genetic engineering, has revolutionized our understanding of life at the molecular level-giving us a detailed picture of the living cell's functions and spawning diverse biotechnologies that use molecules, cells, tissues, and even entire organisms. This introduction to molecular biotechnology is a practical, up-to-date guide to this rapidly growing field. Based on courses taught by the authors to biotechnology professionals, Molecular Biotechnology: Therapeutic Applications and Strategies applies the principles of modern biotechnology to advances and trends in the development of therapeutic strategies and approaches to disease prevention and intervention. By focusing on select applications and strategies, this volume exemplifies the convergence of biological, chemical, and informational advances in the discovery of novel targets and drugs. This multidisciplinary approach, essential to the development of commercial therapeutic molecules, includes carefully selected real-world examples from the pharmaceutical and biotechnology industries. Specific topics covered include: * Genome Based Medicine and the Human Genome Project * Human Gene Therapy * Combinatorial Chemistry * Rational Drug Design * Reengineering the Immune System User-friendly and organized for maximum understanding, Molecular Biotechnology: Therapeutic Applications and Strategies is an excellent text/reference for biotechnology professionals, researchers, physicians, students, managers, industry analysts, and investors interested in learning more about the field of molecular biotechnology.

The second edition explains the principles of recombinant DNA technology as well as other important techniques such as DNA sequencing, the polymerase chain reaction, and the production of monclonal antibodies.

The book will be useful for undergraduate students as a supplementary/reference text in the field of molecular biotechnology.

A study of recent developments in molecular biology and biotechnology, including enzyme technology, genetics and various applications, for example in fermentation technology, protein technology, genetic engineering and product recovery.

Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. - Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology - Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation - Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: - Updated and increased coverage of real time PCR and the mathematics used to measure gene expression - More sample problems in every chapter for readers to practice concepts