This Second Edition of Dr. Katz's highly acclaimed text has been thoroughly revised to incorporate the latest advances in the study and treatment of heart failure. The book explains the pathophysiology, molecular mechanisms, clinical manifestations, and therapy of heart failure in an integrated, reader-friendly manner that is accessible to both clinicians and basic scientists. More than 100 illustrations, most created for this book by the authors, complement the text. This edition has been completely reorganized. Chapters describe the hemodynamic basis for the clinical manifestations of heart failure; the neurohumoral responses in heart failure and key signaling pathways that mediate functional responses; the proliferative responses in failing hearts; the cellular and molecular abnormalities in the failing heart; the rationale for various therapeutic approaches; and the management of specific groups of patients. The chapters on therapy have been written by a noted clinician, Marvin A. Konstam.

Who was the first to write about a certain disease, diagnose it, and treat it? This book answers those questions for a wide range of diseases, from Abetalipoproteinemia to Zollinger-Ellison syndrome. What were the medical practitioners of previous generations hoping to achieve? What were their patients expecting of them? The answers are found in these quotations. Containing over 3,000 entries, and now updated with more than 450 new quotations, this new edition of ""Medicine in Quotations"" is the most comprehensive collection of its type published in over 30 years. It is much more than a random collection of famous sayings relating to sickness and health, disease and treatment; it is a portrait of medicine throughout recorded history. You will discover how medical concepts and practices have developed and shifted through the millennia, and how many illnesses recognized today were first identified a thousand or more years ago. Quotations are organized by topic, and each is fully referenced, allowing curious readers to return to the original source. Subject and author indices make it easy to find quotations of interest. ""Medicine in Quotations"" is an invaluable resource for writers, speakers, and all those interested in the history of medicine.

The story told in this book begins in about 1700, when the first attempts were made to study the diseased heart in life (the subject matter of cardiology), as distinct from its appearance after death; it ends, rather arbitrarily, in 1970. The account of the development of knowledge of heart disease is mainly chronological with emphasis on the fruitful consequences of the cross-fertilization of clinical practice with pathological anatomy at the beginning of the nineteenth century and with physiology at the end. In addition, shorter chapters deals with such topics as specific disease entities, methods of investigation, cardiac surgery and the work of two individuals - Peter Latham, an example of a physician practising with today's clinical skills but a very imperfect knowledge of the pathogenesis of heart disease and Etienne Marey, an early exponent of the clinical physiology which would, in time, throw light on that pathogenesis.

A biography of the English physician and scientist and a history of the advancement of science in the Victorian era. In Victorian Britain, scientific medicine encompassed an array of activities, from laboratory research and the use of medical technologies through the implementation of sanitary measures that drained canals and prevented the adulteration of milk and bread. Although most practitioners supported scientific medicine, controversies arose over where decisions should be made, in the laboratory or in the clinic, and by whom—medical practitioners or research scientists. In this study, Terrie Romano uses the life and eclectic career of Sir John Burdon Sanderson (1829-1905) to explore the Victorian campaign to make medicine scientific. Sanderson, a prototypical Victorian, began his professional work as a medical practitioner and Medical Officer of Health in London, then became a pathologist and physiologist and eventually the Regius Professor of Medicine at Oxford. His career illustrates the widespread support during this era for a medicine based on science. In Making Medicine Scientific, Romano argues this support was fueled by the optimism characteristic of the Victorian age, when the application of scientific methods to a range of social problems was expected to achieve progress. Dirt and disease as well as the material culture of experimentation —from frogs to photographs—represent the tangible context in which Sanderson lived and worked. Romano’s detailed portrayal reveals a fascinating figure who embodied the untidy nature of the Victorian age’s shift from an intellectual system rooted in religion to one based on science. “A useful entry in the canon of science and public health . . . an antidote to the hubris of recent claims of accomplishment.” —Choice

From the author of How We Die, the extraordinary story of the development of modern medicine, told through the lives of the physician-scientists who paved the way. How does medical science advance? Popular historians would have us believe that a few heroic individuals, possessing superhuman talents, lead an unselfish quest to better the human condition. But as renowned Yale surgeon and medical historian Sherwin B. Nuland shows in this brilliant collection of linked life portraits, the theory bears little resemblance to the truth. Through the centuries, the men and women who have shaped the world of medicine have been not only very human, but also very much the products of their own times and places. Presenting compelling studies of great medical innovators and pioneers, Doctors gives us a fascinating history of modern medicine. Ranging from the legendary Father of Medicine, Hippocrates, to Andreas Vesalius, whose Renaissance masterwork on anatomy offered invaluable new insight into the human body, to Helen Taussig, founder of pediatric cardiology and co-inventor of the original "blue baby" operation, here is a volume filled with the spirit of ideas and the thrill of discovery.