First in a multi-volume work dealing with amphibian biology. This volume discusses the development and structure of amphibian skin, the multiple functions of the skin, the chemistry of skin pigments and secretions, and their importance to amphibians. Also provides a chapter on the biological activity and medical uses of various compounds associated with amphibian skin. Includes references and index. Contributors are internationally acknowledged experts in their field.

Now reissued in paperback with an updated preface by the authors, Biology of Amphibians remains the standard work in its field.

The vertebrate integument arose about 450 million years ago as an ‘armour’ of dermal bony plates in small, jawless fish-like creatures, informally known as the ostracoderms. This book reviews the major changes that have occurred in the vertebrate integument from its beginnings to the present day. Critical questions concerning the origin, structure and functional biology of the bony integument are discussed and intrinsically linked to major steps in vertebrate evolution and phylogeny—the origin of jaws and the origin of teeth. The discussions include the origins of mineralization of major vertebrate skeletal components such as the dermatocranium, branchial arches and vertebral column. The advances that led to the origin of modern fishes and their phylogenetic development are reviewed and include the evolution of fins and replacement of the bony plates with several types of dermal scales. The evolution of reptiles saw a major transformation of the integument, with the epidermis becoming the protective outermost layer, from which the scales arose, while the dermis lay below it. The biological significance of the newly-evolved β-keratin in reptilian scales, among the toughest natural materials known, is discussed in the context of its major contribution to the great success of reptiles and to the evolution of feathers and avian flight. The dermis in many vertebrates is strengthened by layers of oppositely oriented cross-fibres, now firmly entrenched as a design principle of biomechanics. Throughout the book conventional ideas are discussed and a number of new hypotheses are presented in light of the latest developments. The long evolutionary history of vertebrates indicates that the significance of the Darwinian concept of “survival of the fittest” may be overstated, including in our own mammalian origins and that chance often plays a major role in evolutionary patterns. Extensive illustrations are included to support the verbal descriptions. Professor Theagarten Lingham-Soliar is in the Department of Life Sciences at the University of KwaZulu-Natal.

**Selected for Doody's Core Titles® 2024 in Veterinary Medicine** Known as "the bible" of herpetological medicine and surgery, Mader's Reptile and Amphibian Medicine and Surgery, 3rd Edition edited by Stephen Divers and Scott Stahl provides a complete veterinary reference for reptiles and amphibians, including specific sections on practice management and development; taxonomy, anatomy, physiology, behavior, stress and welfare; captive husbandry and management including nutrition, heating and lighting; infectious diseases and laboratory sciences; clinical techniques and procedures; sedation, anesthesia and analgesia; diagnostic imaging; endoscopy; medicine; surgery; therapy; differential diagnoses by clinical signs; specific disease/condition summaries; population health and public health; and legal topics. Well-organized and concise, this new edition covers just about everything related to reptiles and amphibians by utilizing an international array of contributing authors that were selected based on their recognized specialization and expertise, bringing a truly global perspective to this essential text!

The integument plays an important role in the survival of meta zoans by separating and protecting them from a hostile environ ment. Its function ranges from protection against injury and in fection, participation in the regulation of body temperature and water balance, to respiratory activity, monitoring of the environ ment and production of signals related to behaviour. All these result from specific structural, biochemical and physiological properties of intra-and extracellular components of the integu ment. Thus its characterization can be best accomplished by a multidisciplinary approach with authors specialized in different fields of science. This multi-author book, in two volumes, provides an up-to date survey of the literature. The first volume deals with the integument of invertebrates, the second with that of vertebrates, both organized primarily on a phylum basis. As the level of knowledge on the integument of phyla differs considerably, the information provided is correspondingly either limited or con densed. For some of the smaller groups of invertebrates little information is available, as often only a few electron micrographs are to be found in the literature ; on the other hand, from the large body of knowledge existing for vertebrates, particularly for mammals, no complete overview can be provided, but publica tions giving access to further information have been reviewed critically.

The first book to systematically integrate knowledge about the endothelium from different organ-specific disciplines.

With an emphasis on the disease conditions of dogs, cats, horses, swine, cattle and small ruminants, Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, 6th Edition continues its long tradition of being the most comprehensive reference book on common domestic mammal pathology. Using a body systems approach, veterinary pathology experts provide overviews of general system characteristics, reactions to insult, and disease conditions that are broken down by type of infectious or toxic insult affecting the anatomical subdivisions of each body system. The sixth edition now boasts a new full-color design, including more than 2,000 high-resolution images of normal and abnormal organs, tissues, and cells. Updated content also includes evolved coverage of disease agents such as the Schmallenberg virus, porcine epidemic diarrhea virus, and the porcine deltacoronavirus; plus new information on molecular-based testing, including polymerase chain reaction (PCR) and in-situ hybridization, keep you abreast of the latest diagnostic capabilities. - Updated content includes new and evolving pathogens and diagnostic techniques. - Updated bibliographies give readers new entry points into the rapidly expanding literature on each subject. - NEW! High-resolution color images clearly depict the diagnostic features of hundreds of conditions. - NEW! Introduction to the Diagnostic Process chapter illustrates the whole animal perspective and details the approaches to systemic, multi-system, and polymicrobial disease. - NEW! Coverage of camelids is now included in the reference's widened scope of species. - NEW! Team of 30+ expert contributors offers the latest perspective on the continuum of issues in veterinary pathology. - NEW! Expanded resources on the companion website include a variety of helpful tools such as full reference lists with entries linked to abstracts in Pub Med and bonus web-only figures. - NEW! Full-color design improves the accessibility of the text.