Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question "How?" to also answering "Why?" Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process. Reviews neuromuscular physiology and the pathology of major diseases. Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states. Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves. Features video clips of waveforms and of ultrasound images to illustrate key concepts. An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine. An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?” Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process. Reviews neuromuscular physiology and the pathology of major diseases. Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states. Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves. Features video clips of waveforms and of ultrasound images to illustrate key concepts. An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Neuromuscular Disorders: A Symptoms and Signs Approach to Differential Diagnosis and Treatment is a practical, evidence-based guide to diagnosis and management of neuromuscular disorders for clinicians. Taking a signs and symptoms approach to the myriad of muscle and nerve problems encountered in the clinic or on the wards, the book provides a roadmap for assessing and localizing weakness, pain, and other disease hallmarks, making an accurate diagnosis, and effective management. Neuromuscular Disorders features bulleted outlines for targeted access to key information and is peppered with useful tables and figures for quick reference. Chapters are written by neuromuscular specialists and are structured to cover the history, clinical investigation, differential diagnosis, and treatment for each disorder. Unlike other texts that begin with diagnosis and work backwards, this concise point-of-care reference starts with presenting complaints and findings to guide the reader along the diagnostic pathway. This approach is the foundation of neurologic practice, and this book will be a valued companion for anyone who suspects a neuromuscular pathology in a patient. Key Features A unique, practical reference for clinicians Symptoms and signs approach to the diagnosis and treatment of neuromuscular disorders Delivers the need-to-know information for successfully identifying and treating both common and rare neuromuscular disorders Structured bullet-point format with tables, diagrams, and algorithms for quick access to essential content

A concise and practical guide to the electrodiagnostic procedures in current use for the investigation of patients with neuromuscular disease. Covers basic and clinical aspects of these diseases and related electrodiagnostic techniques, with special sections focusing on nerves in the upper limbs, nerves in the lower limbs, cranial nerves and the central nervous system. Third edition of this classic text - designed for students and neurologists who occasionally use EMG and a quick reference for experienced electromyographers - contains seven all-new chapters of expanded clinical materials and a useful and complete glossary. Covers scope and limitations of EMG procedures Explains apparatus used for electrodiagnostic study Emphasizes both clinical applications of current techniques and their physiologic basis Discusses all the latest advances in this fast-growing field Offers precise guidelines for practical application of techniques in a clinical setting I have no hesitation in recommending the book to clinical neurophysiologists and to their clinical colleagues striving to assess the relevance of test results." Journal of Neurology, Neurosurgery and Psychiatry "Tables and illustrations are very good and the general presentation is notably clear. This book is eminently suitable as an introduction to electromyography for neurologists and clinical neurophysiologists." Brain"

This new two-volume reference offers a practical approach to diseases of the muscle, neuro-muscular junction, and spinal cord. Volume I emphasises the pathophysiology of neuromuscular disease and its assessment using electrophysiological and radiological tools. Volume II focuses on the application of electrophysiological testing to the diagnosis and management of specific neuromuscular disorders. Edited by three respected experts, this essential resource also explores HIV, clinical trials, and neuromuscular disorders in critical care and the operating room. Integrates all the guidance needed to diagnose and manage the full range of neuromuscular diseases. Enhances the reader's ability to take neuromuscular histories, perform physical examinations, order and interpret laboratory tests, make effective management decisions and offer patients an accurate prognosis. Discusses new advances in electrophysiologic tests as well as genetic testing and the use of MRI to localize and diagnose neuromuscular conditions. Examines new management techniques such as the use of immunosuppressive drugs to treat Guillain-Barré syndrome, immune mediated peripheral neuropathy, myasthenia gravis and more. Features coverage of important topics such as HIV, clinical trials and neuromuscular disorders in critical care and the operating room. Details both adult and paediatric neuromuscular disorders. Reviews the basic science and genetics practicing physicians need to care effectively for their patients.

Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.