One in five people in the United States had a sexually transmitted infection (STI) on any given day in 2018, totaling nearly 68 million estimated infections. STIs are often asymptomatic (especially in women) and are therefore often undiagnosed and unreported. Untreated STIs can have severe health consequences, including chronic pelvic pain, infertility, miscarriage or newborn death, and increased risk of HIV infection, genital and oral cancers, neurological and rheumatological effects. In light of this, the Centers for Disease Control and Prevention, through the National Association of County and City Health Officials, commissioned the National Academies of Sciences, Engineering, and Medicine to convene a committee to examine the prevention and control of sexually transmitted infections in the United States and provide recommendations for action. In 1997, the Institute of Medicine released a report, The Hidden Epidemic: Confronting Sexually Transmitted Diseases. Although significant scientific advances have been made since that time, many of the problems and barriers described in that report persist today; STIs remain an underfunded and comparatively neglected field of public health practice and research. The committee reviewed the current state of STIs in the United States, and the resulting report, Sexually Transmitted Infections: Advancing a Sexual Health Paradigm, provides advice on future public health programs, policy, and research.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Multidisciplinary collection of essays on the relationship of infertility and the "historic" STIs--gonorrhea, chlamydia, and syphilis--producing surprising new insights in studies from across the globe and spanning millennia.

One of the greatest challenges faced by William Clark and Meriwether Lewis on their 1804?6 Corps of Discovery expedition was that of medical emergencies on the trail. Without an attending physician, even routine ailments and injuries could have tragic consequences for the expedition?s success and the safety of its members. Of these dangers, the most insidious and potentially devastating was the slow, painful, and oftentimes fatal ravage of venereal disease. ø Physician Thomas P. Lowry delves into the world of nineteenth-century medicine, uncovering the expedition?s very real fear of venereal disease. Lewis and Clark knew they were unlikely to prevent their men from forming sexual liaisons on the trail, so they prepared for the consequences of encounters with potentially infected people, as well as the consequences of preexisting disease, by stocking themselves with medicine and the latest scientific knowledge from the best minds in America. Lewis and Clark?s expedition encountered Native peoples who experienced venereal disease as a result of liaisons with French, British, Spanish, and Canadian travelers and had their own methods for curing its victims, or at least for easing the pain it inflicted. ø Lowry?s careful study of the explorers? journals sheds new light on this neglected aspect of the expedition, showing in detail how sex and venereal disease affected the men and their mission, and describes how diverse peoples faced a common threat with the best knowledge and tools at their disposal.

Male genital disorders represent a common issue in medical practice, especially in the dermatological setting. Correct clinical evaluation of these disorders is essential when addressing the diagnosis, which in some cases may require histopathological confirmation. Depending on the disease, early diagnosis may be not only lifesaving, but also of fundamental importance to the planning of successful treatment. This atlas introduces the most common penile diseases, along with more rarely encountered ones. It provides invaluable guidance on clinical diagnosis by highlighting prominent clinical features and presenting particular videodermatoscopy findings when these are indicative of the diagnosis. In addition, for each condition the most appropriate treatment is proposed, taking into account recent therapeutic advances of proven benefit.