This issue of Veterinary Clinics: Small Animal Practice, edited by Dr. Ciara Barr and Dr. Giacomo Gianotti, focuses on Alternatives to Opioid Analgesia in Small Animal Anesthesia. Topics include: Immunomodulatory Effects of Opioids in Cancer Patients; NSAIDs; Alpha-2 Agonists; Acupuncture and Alternative Medicine; Loco-regional Anesthesia of the Head; Loco-regional Anesthesia of the Front Limbs and Thorax; Loco-Regional Anesthesia of the Hind Limbs; Epidural and Spinal Anesthesia; Local Anesthesics (Nocita); Adjuvants to Analgesia; and Physical Therapy.

This issue of Veterinary Clinics: Small Animal Practice, guest edited by Drs. Beth Marchitelli and Tami Shearer, focuses on Small Animal Euthanasia: Updates on Clinical Practice. This is one of six issues each year. Articles in this issue include, but are not limited to: historical perspective of euthanasia in veterinary medicine, the science of transitional states of consciousness and euthanasia, the physiology of death, pharmacological methods: an update on optimal pre-sedation and euthanasia solution administration, common and alternative routes of euthanasia solution administration, standardization of data collection to document adverse events associated with euthanasia, factors contributing to the decision to euthanize: diagnoses, clinical signs and triggers, euthanasia decision making: a collaboration between pet owners and veterinary professionals, euthanasia from the veterinary client's perspective: psychosocial contributors to euthanasia decision-making, and communication and euthanasia- beyond open ended questions

This issue of Veterinary Clinics: Small Animal Practice, edited by Dr. Annette Litster, is devoted to Small Animal Infectious Disease. Topics in this issue include: The dynamic nature of infectious disease risk in the 21st century: How dog transport impacts prevalence patterns; Dog transport and infectious disease risk: an international perspective; Effect of dog transport on high-risk infectious diseases (e.g. TVT, rabies etc.); H3N8 and H3N2; Feline panleukopenia: a re-emergent disease; Canine Lyme disease immunology; Canine leptospirosis diagnostics; Canine ehrlichiosis in the USA; Cutaneous and Renal Glomerular Vasculopathy (CRGV; Alabama Rot); Vector borne disease panel diagnostics; Feline vector-borne diseases; Canine brucellosis; and Current preventative strategies for rabies.

This issue of Veterinary Clinics: Small Animal Practice, guest edited by Drs. Karl Maritato and Matthew Barnhart, focuses on Minimally Invasive Fracture Repair. Articles in this issue include, but are not limited to: Biomechanics of Fracture Fixation; Challenges in Minimally Invasive Fracture Repair; Minimally Invasive Osteosynthesis Fracture Reduction Techniques; Percutaneous Pinning for Fracture Repair; Minimally Invasive Plate Osteosynthesis Techniques for the Humerus; Minimally Invasive Plate Osteosynthesis Techniques for the Radius and Ulna; Minimally Invasive Osteosynthesis (MIO) Techniques of the Femur; Minimally Invasive Osteosynthesis Techniques for Articular Fractures; Unique Differences of Minimally Invasive Fracture Repair in the Feline; Perioperative Imaging in Minimally Invasive Osteosynthesis; Interlocking Nails for Minimally Invasive Osteosynthesis; Minimally Invasive Plate Osteosynthesis Techniques for Tibia and Fibula; Minimally Invasive Plate Osteosynthesis Techniques for Meta-bones; Minimally Invasive Osteosynthesis Techniques for Sacroiliac Luxation; and Minimally Invasive Plate Osteosynthesis Techniques for Arthrodesis.

This issue of Veterinary Clinics: Small Animal Practice, edited by Dr. Philip Bergman and Dr. Craig Clifford, focuses on Cancer in Companion Animals. Topics include: Novel Non-Invasive Diagnostics; MCT: Cytologic and Histologic Grading Update; Sentinel LN & Sx Oncology Update; RT Oncology Update; Novel Prescriptions for LSA; Targeted Prescriptions Update; Electrochemotherapy; Tumor Ablation; Anorexia and the Cancer Patient; Histiocytic Sarcome and HSA; Cancer Immunotherapies; and Personalized Cancer Medicine.

This issue of Veterinary Clinics: Small Animal Practice, edited by Dr. Katherine J. Goldberg, focuses on Advances in Palliative Medicine. Article topics indlue: Pet Hospice Program at Colorado State University; Hospice Care Service at Michigan State University; Pain and Palliative Care Service at Angell Memorial Animal Hospital; Current topics in serious illness and palliative medicine: a curricular initiative at Cornell University; Development and use of the Serious Veterinary Illness Conversation Guide; Ethics of palliative medicine in veterinary patients; Overcoming obstacles to palliative care: what can we learn from our MD colleagues?; Caregiver burden and veterinary client mental health concerns; Capacities of animal patients: how cognitive ethology can (and should) inform palliative and end of life care; Palliative care challenges from the oncology service in a veterinary teaching hospital; Private practice oncology: viewpoint on end of life decision-making; Advances in pain management, palliative care applications; Advances in neurology, palliative care applications; Updates and advances in cognitive dysfunction; Perspectives on nutrition and feeding; Palliative care services at home: viewpoint from a multi-doctor practice; Objective exploration of euthanasia: what do (and don’t) we know about adverse effects?; Integrating a social worker into the veterinary team for palliative care and hospice; and Conflict management.

This issue of Veterinary Clinics: Small Animal Practice, guest edited by Dr. Lynelle Johnson, is an update on Canine and Feline Respiratory Medicine. This is one of six issues each year. Articles in this issue include, but are not limited to: updates on pulmonary function testing in small animals, laryngeal disease in dogs and cats, chronic rhinitis in the cat, feline aspergillosis, canine nasal disease, update on feline asthma, canine chronic bronchitis, tracheal and airway collapse in dogs, idiopathic pulmonary fibrosis in west highland white terriers, bacterial pneumonia in dogs and cats, and exudative pleural diseases in small animals.