"Give me a baby, Orion." "Make a baby with me." Standing close the door to my chamber, I noticed my Luna, Petra, enjoying wild s*x with my Beta, Orion. Three years of mate bonding, as well as fifteen years of friendship and trust, were shattered at that instant. After three years of betrayal and covert love with my Beta, this woman pleaded for mercy: "1, Xavier Lincoin, the Alpha of Sirius Bright pack reject, Petra Lincoin as my mate, and Luna."

Richard Dallas is an Alpha but he is also an Alpha in NEED. With all the women in his pack now barren he has no choice but to hire a human female to be surrogate and produce a cub for him. Little did he know he would find love at the same time.... When Reign accepted the job of being a surrogate for a handsome yet very mysterious man she did wonder if everything was as it seemed. She really had no idea that she was not going to be any ordinary surrogate, she was going to be the Alpha's surrogate and her job was set to be even more important then she could ever have imagined. However, with the importance of the surrogacy also brings grave danger. There are others who have a strong interest in this special baby and it is down to Richard to protect Reign by any means necessary. To do so, she must go and live with him so he can take care of her in more ways then just one...

A limited time opportunity to own ALL FIVE books from the bestselling paranormal pregnancy romance series, "THE SURROGATES" and all for one low, low price! Every book in the series has been a top #10 bestseller on Amazon.com and is a complete novel with no cliffhangers! In a world where some shapeshifters are having trouble reproducing they have to turn to fertile women to be surrogate mothers to their shape-shifting babies. Some of these women know what they are letting themselves in for, whilst some have absolutely no idea! Every book follows the fortunes of a different heroine as she is used for reproduction by a handsome shapeshifter... Expect Romance, Thrills, Spills, Action, Adventure and, of course, sensual scenes! BOOK 1 - THE ALPHA'S SURROGATE With all the women in his pack now barren Alpha Wolf Richard Dallas has no choice but to hire a human female to be surrogate and produce a cub for him. When Reign accepted the job of being a surrogate she had no idea that she was going to be the Alpha's surrogate and her job was set to be even more important then she could ever have imagined. However, with the importance of the surrogacy also brings grave danger and so she must go and live with the Alpha so he can take care of her in more ways then just one... BOOK 2 -THE BEAR'S SURROGATE WereBear Alpha Valemon has found there is a curse on his tribe that only a new born bear cub could cure. So he hires an unwitting human female called Rachel to be his Surrogate. Rachel is more than ready for the ride but she did not expect that Valemon insisted the baby be conceived naturally... BOOK 3 - THE DRAGON'S SURROGATE Tasha has been seeking a role as a surrogate mother for sometime now but it has not been easy. However, now she has hit the jackpot as a wealthy man is offering a huge reward in exchange for carrying his child. However, what Tasha did not expect was that this man would be a dragon shifter and also the most handsome man she had ever seen.... BOOK 4 - THE LION'S SURROGATE With WereLions on the brink of extinction, Lion King Torrance has a big challenge on his hand in finding a human woman with a special gene capable of carrying a shifter baby. That woman is curvy Amy and now Torrance must do all he can to persuade her to be his surrogate... BOOK 5 - THE PANTHER'S SURROGATE WerePanther Kheem knows he needs to reproduce soon but he can not wait any longer to try and find the perfect mate. So he approaches Josie with a proposition that she be his surrogate mother. Considering they used to date this could be the perfect situation. However, there is another reason he has chosen her and when further danger arrives this reason soon becomes apparent to everyone... You simply will not be able to put these books down! Scroll back up and start reading the whole package right away!

THE SELKIE PRINCE’S FATED MATE (book 1): A Selkie prince forced to produce an heir. An omega destined to become a royal’s fated mate... Prince Kai’s life as he knows it is now over. As the firstborn alpha to the Selkie King of the North, he’s required to produce an heir. Whether he wants to or not. When the Selkie Seekers finally present his fated mate, he dreads being tied to this stranger for the rest of his life. He can only hope his omega will be easy on the eyes and somewhat intelligent. Raised in a family of good breeding, Luca always knew it was possible he’d end up the mate for an alpha of nobility. Only to whom, he never knew. Every time the Seekers summoned him for the humiliating presentation ceremony to royalty of all levels, he feared being stuck with some unbearable, abusive or very unattractive alpha. As an omega he doesn’t have the choice to say no. Not only is it his obligation, it’s the law. If he refuses, he and his family would become outcasts and banished from the Selkie community. However, as soon as Kai enters the Great Hall of the North, it’s clear that the handsome prince is his alpha. Luca’s pleased with the choice the fates made until the king demands that not only he become pregnant within six months but produce an alpha pup with his son, otherwise he’ll be cast aside. And getting pregnant might be a problem... THE SELKIE PRINCE & HIS OMEGA GUARD (book 2): An alpha prince ready to find his fated mate. A Selkie who wishes he wasn’t omega-born... Unlike his brothers, Prince Adrian, the dutiful second-born son to the King of the North, looks forward to finding his true mate and producing an heir. Until he stumbles across a beta guard with an enticing scent. Del never wanted to be an omega. All his life, he’s only wanted one thing: to serve as a Royal Guard. Though forbidden, he found a concoction to mask his omega scent and was successful until his dwindling supply caused the alpha prince to discover his deception. Rian not only breaks every cherished royal tradition, but ends up hiding Del until he can figure out the reason for the attraction between them. However, one selfish mistake puts them in a precarious position they can’t escape. Their reckless actions have them worried they’ll be banished from the Selkie community. Rian needs a plan to convince his father to accept his mate before he has to risk everything he’s ever known and loved for their future. Because, no matter what the king says, Rian will not give up Del. THE SELKIE PRINCE’S UNEXPECTED OMEGA (book 3) An alpha claim. A possible heir. A Selkie prince whose mistake might just be what the fates intended. Zale, the third alpha-born son of King Solomon, is concerned. His youngest brother, Caol, has been spending time with an unbonded omega. Being a responsible alpha, Zale feels it’s his duty to warn the omega Finn before he and Caol get into trouble. Especially since Finn had only been brought to the colony by their father in case his oldest brother’s fated mate couldn’t conceive. However, when Zale goes to Finn’s quarters to have a word with him, he isn’t expecting to discover what he does: the omega in the throes of oestrus and begging for an alpha’s assistance. Finn has nowhere else to go. Not only unwanted by his own family, his previous alpha perished in a tragic accident. So for the past two years, the omega has relied on the King of the North’s generosity, even if it means he may end up as a surrogate for one of the alpha-born princes. Or even worse, the king’s sixth mate. But when the Prince Zale comes upon him during his heat, Finn demands relief from the alpha. Although afterward, has to live with the guilt. Now, he might not only be carrying the prince’s son, he may have very well ruined Zale’s chance to find his true fated mate... Note: This collection includes m/m shifter mpreg stories. Due to the “knotty” times in these books, they’re recommended for mature readers only. While they can be read as standalones, it’s recommended to read the series in order. And, like all of my books, each has an HEA.

New genomic information has revealed the crucial role that protein-protein interactions (PPIs) play in regulating numerous cellular functions. Aberrant forms of these interactions are common in numerous diseases and thus PPIs have emerged as a vast class of critical drug targets. Despite the importance of PPIs in biology, it has been extremely challenging to convert targets into therapeutics and targeting PPIs had long been considered a very difficult task. However, over the past decade the field has advanced with increasing growth in the number of successful PPI regulators. Protein-Protein Interaction Regulators surveys the latest advances in the structural understanding of PPIs as well as recent developments in modulator discovery.

Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. - Provides documentation of the variations in clinical presentation and pathology in a single reference - Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease - Allows for easy reference for the diagnosis of AATD to lead to better therapeutics

Data Warehousing for Biomedical Informatics is a step-by-step how-to guide for designing and building an enterprise-wide data warehouse across a biomedical or healthcare institution, using a four-iteration lifecycle and standardized design pattern. It enables you to quickly implement a fully-scalable generic data architecture that supports your organization's clinical, operational, administrative, financial, and research data. By following the guidelines in this book, you will be able to successfully progress through the Alpha, Beta, and Gamma versions, plus fully implement your first production release in about a year.