This book reflects on current thinking in development economics and on what may happen over the next two decades. As well as studying development economics in retrospect, the volume explores the current debates and challenges and looks forward at the problems that affect the global capacity to achieve the Millennium Development Goals.

A Guide for governments and stakeholders seeking to strengthen the contribution of sport to development and peace work. Part 1 provides evidence-based analysis of the potential contribution of sport to development objectives. Part 2 provides a practical framework for analysis, planning and monitoring of sport in development and peace work.

This book focuses on an “outside the box” notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)–N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.

Within the field of academic development, the last twenty years have seen a great expansion of published research into practice and the further development of theoretical approaches. This growth in the scholarship of academic development matches a growth in the scholarship of teaching and learning. Advancing Practice in Academic Development draws on these evolving scholarships to advance professional practice in academic development, addressing questions such as: . How have global academic developers and their units developed and changed over recent decades? How has the context in which academic development work is done altered? What have academic developers and their professional associations learnt? Case studies and examples are used throughout the text to illustrate development scenarios and methods. Academic development is considered as, among others, a critical, a scholarly, a principled, a pragmatic, a supporting and a leadership role. This book is ideal for use on academic development courses run by SEDA and other international organisations as well as by those who have responsibility for leading the improvement of educational practice. Written in a scholarly, accessible, stimulating and practical style, this book acknowledges difficulties and offers ways forward. As well as analysing problems, it offers solutions. Links to web sources referenced in this book can be found at www.seda.ac.uk/apad

Advanced Analysis of Motor Development explores how research is conducted in testing major issues and questions in motor development. It also looks at the evolution of research in the field, its current status, and possible future directions. This text is one of the few to examine motor development models and theories analytically while providing a context for advanced students in motor development so they can understand current and classic research in the field. Traditionally, graduate study in motor development has been approached through a compilation of readings from various sources. This text meets the need for in-depth study in a more cohesive manner by presenting parallels and highlighting relationships among research studies that independent readings might not provide. In addition, Advanced Analysis of Motor Development builds a foundation in the theories and approaches in the field and demonstrates how they drive contemporary research in motor development. A valuable text for graduate students beginning their own research projects or making the transition from student to researcher, this text focuses on examining and interpreting research in the field. Respected researchers Haywood, Roberton, and Getchell explain the history and evolution of the field and articulate key research issues. As they examine each of the main models and theories that have influenced the field, they share how motor development research can be applied to the fields of physical education, special education, physical therapy, and rehabilitation sciences. With its emphasis on critical inquiry, Advanced Analysis of Motor Development will help students examine important topics and questions in the field in a more sophisticated manner. They will learn to analyze research methods and results as they deepen their understanding of developmental phenomena. For each category of movement skills covered (posture and balance, foot locomotion, ballistic skills, and manipulative skills), the authors first offer a survey of the pertinent research and then present an in-depth discussion of the landmark studies. In analyzing these studies, students will come to appreciate the detail of research and begin to explore possibilities for their own future research. Throughout the text, special elements help students focus on analysis. Tips for Novice Researchers sidebars highlight issues and questions raised by research and offer suggestions for further exploration and study. Comparative tables detail the differences in the purpose, methods, and results of key studies to help students understand not only what the studies found but also the relevance of those findings. With Advanced Analysis of Motor Development, readers will discover how research focusing on the major issues and central questions in motor development is produced and begin to conceptualize their own research. Readers will encounter the most important models and theories; dissect some of the seminal and recent articles that test these models and theories; and examine issues such as nature and nurture, discontinuity and continuity, and progression and regression. Advanced Analysis of Motor Development will guide students to a deeper understanding of research in life span motor development and enable them to examine how the complexities of motor development can be addressed in their respective professions.

Since the early 2000s, state-led and innovation-focused strategies have characterized the approach to development pursued in countries around the world, such as China, India, and South Korea. Brazil, the largest and most industrialized economy in Latin America, demonstrates both the opportunities and challenges of this approach. Over the course of nearly 20 years, the Brazilian government enacted various policies and programs designed to strengthen the country’s capacity to innovate. It increased spending on science and technology, encouraged greater collaboration between industry and universities, and fostered the creation of new institutions whose primary aim was to facilitate greater private research and development (R&D) spending. In this book, the editors unite a diverse array of empirical contributions around a few key themes, including public policies, institutions and innovation ecosystems, and firms and industries, that collectively make the case for a new, forward-looking innovation agenda aimed at addressing persistent challenges and exploiting emerging opportunities in Brazil. Its conclusions offer valuable lessons for other developing and emerging economies seeking to accelerate innovation and growth in the modern age. With its interdisciplinary and wide-ranging contribution to the study of innovation, as well as attention to broader policy implications, this book will appeal to scholars and professionals alike.

This book explores the potential responsibilities to respect, protect and fulfill international human rights law (IHRL) of a particular class of non-state actors: non-governmental organizations (NGOs). It calls for NGOs pursuing development to respect and fulfill the human right of genocide survivors to reparative justice in Rwanda. It argues that NGOs have social and moral responsibilities to respect and fulfill IHRL, and for greater accountability for them to do so. The book focuses on those NGOs advancing development in a post genocide transitional justice context acting simultaneously in partnership with state governments, as proxies and agents for these governments, and providing essential public goods and social services as part of their development remit. It defines development as a process of expanding realization of social, economic, and cultural rights addressing food security, economic empowerment/poverty reduction, healthcare, housing, education, and other fundamental human needs while integrating these alongside the expansion of freedoms and protections afforded by civil and political rights. It uses post genocide Rwanda as a case study to illustrate how respect and fulfillment of the IHRL pertaining to reparative justice are hindered by failing to hold NGOs responsible for IHRL. Consequently, this results in discrimination against, marginalization, and the disadvantaging of survivors of the Rwandan genocide against the Tutsi and violations of their human rights.