Advances in Surgical Pathology: Mesothelioma, a volume in the Advances in Surgical Pathology series, features chapters on current and impending changes in the field with an emphasis on practical issues, recent developments, and emerging concepts. Created as a quick review, this volume delivers a concise, updated review of the pathological characteristics of mesothelioma—emphasizing the histologic correlation, clinical management, and treatment of the disease. Timely content features include recognition of precursor mesothelial lesions, the role of molecular biology in the diagnosis and prognosis of mesothelioma, the interface between the clinician and the surgical pathologist, and the legal implications of attributing disease origin to asbestos and other factors. The book provides a resource for the periodic updates in knowledge required for daily practice, for current credentialing, and for the self-assessment modules for recertification.

"This volume of the Advances in Surgical Pathology Series is a concise, updated review of the pathological characteristics of mesothelioma. It emphasizes the histologic correlation, clinical management, and treatment of mesothelioma. It features current and emerging concepts in the field, which includes recognition of precursor mesothelial lesions, the role of molecular biology in the diagnosis and prognosis of mesothelioma, the interface between the clinician and the surgical pathologist, and the legal implications in relation to disease attributibility to asbestos and other factors. The book provides a resource for the timely updates in knowledge that are necessary for daily practice, for current credentialing, and for the self-assessment modules for recertification (MOC)."--Provided by publisher.

"This volume of the Advances in Surgical Pathology Series is a concise, updated review of the pathological characteristics of mesothelioma. It emphasizes the histologic correlation, clinical management, and treatment of mesothelioma. It features current and emerging concepts in the field, which includes recognition of precursor mesothelial lesions, the role of molecular biology in the diagnosis and prognosis of mesothelioma, the interface between the clinician and the surgical pathologist, and the legal implications in relation to disease attributibility to asbestos and other factors. The book provides a resource for the timely updates in knowledge that are necessary for daily practice, for current credentialing, and for the self-assessment modules for recertification (MOC)."--Provided by publisher.

This book provides essential information on recent advances in molecular genetics, epidemiology, translational research, and the latest results of clinical trials on mesothelioma. Significant progress has been made in understanding mesothelioma biology, and in developing new therapies for this refractory tumor, malignant pleural mesothelioma (MPM). Not only does this volume summarize the latest research-based data on the disease; it also shares insights into future research directions. The book consists of 5 themed sections on: epidemiology, pathogenesis, screening and early detection, molecular genetics, and clinical aspects and management. Several chapters focus on new trends in the field, e.g. immune therapy and identification of biomarkers, molecular oncogenesis including genetic susceptibility, and molecular diagnostic pathology. The book also highlights new cancer treatment approaches, such as immunotherapy based on immune checkpoint inhibitors, which has meant a paradigm shift in other types of cancer, and given some hope to MPM patients. In turn, it discusses recent molecular pathological studies on mesothelioma, which claim to offer more accurate classifications than traditional morphology and immunohistochemistry-based approaches. All of these cutting-edge analyses provide the basis for a closing discussion on future developments and research directions. Malignant Pleural Mesothelioma - Advances in Pathogenesis, Diagnosis, and Treatments has been edited and authored by respected researchers and will be of interest to medical, surgical and radiation oncologists; pulmonologists; pathologists and basic researchers alike. Since the disease represents a significant diagnostic and therapeutic challenge, scientists and clinicians from learners to experts, as well as fellows in training in these subspecialties, will value this book.

Advances in Surgical Pathology: Colorectal Carcinoma and Tumors of the Vermiform Appendix, a volume in the Advances in Surgical Pathology series, features chapters on current and impending changes in the field with an emphasis on practical issues, recent developments, and emerging concepts. Created as a quick review to be used during pathologic evaluation of cancer specimens from the lower gastrointestinal tract, this book contains the latest information regarding emerging endoscopic techniques that aid in tumor classification and staging, mechanisms of pathogenesis, and clinical management. It combines gross and microscopic images and user-friendly tables for quick reference with a succinct, comprehensive review of issues important to management of patients with colorectal carcinoma. Not only does it discuss the applied concern of cancer epidemiology and prevention, the book also covers pathological features of cancer precursors. Plus, an introduction to future diagnostic and treatment modalities, such as biomarker analysis, chemotherapeutic strategies, targeted molecular therapies, and aggressive multidisciplinary approaches to patients with advanced stage disease.

• Only up-to-date title in the market • Current topic with significant media coverage • Internationally relevant, the use of asbestos and its consequences is a global problem • This title aids in pathological diagnosis which is very difficult • Contributors are experts from France, UK, USA, Australia and Canada • Plentiful, colored illustrations complete the text • Target group exceeds pathologists: The diagnosis is evidence for medico-legal purposes, which makes the book invaluable to members of legal profession specializing in this disease