The International Symposium on Prostaglandins and Related Compounds, first held in Vienna 1972, revisited the city after 24 years for the 10TH Symposium. For the many re searchers working in this multi-disciplinary field it was an opportunity to exchange their ex periences and share new data with colleagues from all around the world. This scientific exchange was largely encouraged by the unseasonably cold and rainy weather. For the first time, there was quite a large attendance from the former Communist countries. Eugene Garfield prepared a key note address delivered during the meeting (The Sci entist 1996, 12) reviewing the contribution of the Nobel Laureates U.S. von Euler, l.R. Vane, S.K. Bergstrom, and B.I. Samuelsson, discussing the relevance of the more than 40,000 pa pers in this area published since 1991. Overall, there is still a rapidly growing interest, and in particular a great variety of clinical applications of this family of compounds which were dis cussed in detail during the meeting. Beside the lectures there were 19 workshops covering nearly all the topics of key in terest. All the speakers were invited to prepare a manuscript which has resulted in the volume now in your hands. Special thanks to Dr. Patrick Wong and the new publisher of this series who helped to publish the proceedings in the usual quality and reasonable period of time. Looking forward to seeing all of you again in Florence in 1999, hopefully with much more sun.

Prostaglandins, Platelets, Lipids: New Developments in Atherosclerosis focuses on developments pertaining to atherosclerosis and suggested novel approaches for its prevention, treatment, and complications. The selection first underscores the biological importance and therapeutic potential of prostacyclin and rationale for the suppression of platelet aggregation and thrombosis by dietary manipulation of fatty acids. Discussions focus on eicosapentaenoic acid as a potential antithrombotic substance, vascular effects of prostacyclin, antithrombotic and hemostatic effects of prostacyclin, fatty acids, prostacyclin, and thrombosis, and therapeutic uses of prostacyclin. The text then examines prostaglandins and hypertension, role of platelets in stroke and transient ischemic attack, and antiplatelet agents in the prevention of acute coronary events. Topics include thrombosis and clinical complications of atherosclerosis, mechanisms in thrombosis, vascular prostaglandins and antihypertensive mechanisms, and renal prostaglandins and antihypertensive mechanisms. The book ponders on a specific inhibitor of thrombin and cardiovascular actions of prostacyclin in man, including prostacyclin and angina pectoris, prostacyclin therapy for peripheral arterial disease, and hemodynamic changes induced by prostacyclin. The selection is a dependable source of data for researchers interested in atherosclerosis.