In this issue of Gastroenterology Clinics, guest editor Alan L. Buchman brings considerable expertise to the topic of Advances in Intestinal Transplantation. Experts in the field cover topics such as Indications for Intestinal Transplantation, Multivisceral Transplantation, and more. - Contains a variety of relevant topics including Normothermic Preservation of the Intestinal Allograft; Abdominal Wall Closure in Intestinal and Multivisceral Transplantation; Intestinal Transplant for Hirschsprung's Disease; and more. - Provides in-depth clinical reviews on intestinal transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Gastroenterology Clinics, guest editor Dr. Alan L. Buchman brings his considerable expertise to the topic of Advances in Intestinal Transplantation, Part II. In this second of two issues devoted to the comprehensive coverage of this topic, top experts discuss the complexities of intestinal failure (IF) and provide a better understanding of medical and surgical management. Coverage also includes assessment of when patients should be referred to select centers of expertise where both medical and surgical (nontransplant and transplant) modalities are available. - Contains 12 relevant, practice-oriented topics including innate and cellular immune responses in intestinal transplantation: new discoveries: altering the microbiome and implications for host metabolomics; vaccines and vaccine response: other maintenance care in the small bowel transplant patient; living donor intestinal transplantation; the stem cell niche in short bowel syndrome; and more. - Provides in-depth clinical reviews on advances in intestinal transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Gastroenterology Clinics, guest editor Dr. Robert Odze brings his considerable expertise to the topic of Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Tubal Gut, Liver, and Pancreaticobiliary System: A Contemporary Update. Top experts review all the basic advances in the biology of neoplastic precursor lesions and its molecular and clinical implications to provide a better and more uniform understanding of mechanisms of cancer development in the gastrointestinal system and related organs. - Contains 10 relevant, practice-oriented topics including Barrett's esophagus and associated dysplasia; hepatic precancerous lesions and early hepatocellular carcinoma; pathology and clinical significance of inflammatory bowel disease-associated colorectal dysplastic lesions; sporadic colorectal polyps of the colon; pathology of gastrointestinal polyposis disorders; and more. - Provides in-depth clinical reviews on neoplastic precursor lesions of the tubal gut, liver, and pancreaticobiliary system, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Gastroenterology Clinics, guest editor Dr. Lee M. Kaplan brings his considerable expertise to the topic of Management of Obesity, Part 2: Treatment Strategies. Thirteen percent of the world's population are obese, and most of the world's population live in countries where being overweight and obese kills more people than being underweight. In this second issue (of two), key experts address treatment and prevention strategies for obesity, including bariatric surgery, medical management, and lifestyle modifications. - Contains 16 practice-oriented topics including bariatric and metabolic surgery; mechanisms of weight loss and metabolic improvement after bariatric surgery; endoscopic therapies for obesity and its complications; obesity and viral infections including SARS-Cov-2; the future of obesity care; and more. - Provides in-depth clinical reviews on management of obesity, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Gastroenterology Clinics, guest editor Dr. Marla Dubinsky brings her considerable expertise to the topic of Pediatric Inflammatory Bowel Disease. Pediatric patients with IBD become adult patients with IBD, making it imperative that children receive early, effective intervention to optimize their growth and development, minimize disease complications, and support patients on their journey from childhood to adulthood. In this issue, top experts provide up-to-date information that helps provide an evidence-based approach for each patient. - Contains 11 practice-oriented topics including optimizing the transition and transfer of care in pediatric IBD; building a self-management toolkit for pediatric IBD patients; choosing the right therapy at the right time for pediatric IBD: does sequence matter?; the state of clinical trials in pediatric IBD; the role of diet in pediatric IBD; and more. - Provides in-depth clinical reviews on pediatric inflammatory bowel disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

For this important and unique issue of Gastroenterology Clinics, Consulting Editor Dr. Alan Buchman decided to serve as co-Guest Editor with Dr. David Hackam to provide a “bench to bedside look at intestinal failure. Authors have contributed reviews on the status of the science behind artificial organs while emphasizing how to clinically prepare for intestinal failure. Articles are devoted to the following topics: Initial Evaluation and Care of the Patient with New Onset Intestinal Failure; Getting the Patient Ready for Home Parenteral Nutrition; Pediatric Intestinal Failure: Etiology and Management; Predictors of Intestinal Adaptation in Children; Management of the Patient with Chronic Intestinal Pseudo-obstruction and Intestinal Failure; Intestinal Growth and Adaptation Following Resection in Intestinal Failure; Fluid and Electrolyte Management and Prevention of Dehydration in Intestinal Failure; The Oley Foundation and Consumer Support Groups; Weaning from Parenteral Nutrition; Hepatobiliary Complications of Intestinal Failure; Non-Transplant Surgery in Intestinal Failure; Indications for Intestinal Transplantation in Intestinal Failure; Intestinal Regeneration and the Artificial Gut; Bench to Bedside Approaches for Engineered Intestine, Esophagus and Colon; and Fetal and Amniotic Stem Cells in Gut Engineering. Readers will come away with a true state-of-the-art look at how to manage intestinal failure.

In this issue of Gastroenterology Clinics, guest editor Alan L. Buchman brings considerable expertise to the topic of Advances in Intestinal Transplantation. Experts in the field cover topics such as Indications for Intestinal Transplantation, Multivisceral Transplantation, and more. Contains a variety of relevant topics including Normothermic Preservation of the Intestinal Allograft; Abdominal Wall Closure in Intestinal and Multivisceral Transplantation; Intestinal Transplant for Hirschsprung’s Disease; and more. Provides in-depth clinical reviews on intestinal transplantation, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.