This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Àlex Rovira Cañellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!

In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology’s 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging. Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more. Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology's 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging. Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more. Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Neurologic Clinics, edited by Dr. Darin T. Okuda, focuses on Multiple Sclerosis. Topics include, but are not limited to, Myelin and Axonal Repair Strategies in Multiple Sclerosis; Common Clinical and Imaging Conditions Misdiagnosed as Multiple Sclerosis; Topographical Model for Multiple Sclerosis: A Novel Approach to Understanding Clinical Phenotypes and Disease Activity; Incidental Anomalies Characteristic of CNS Demyelination: Radiologically Isolated Syndrome; Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management; Progressive Forms of Multiple Sclerosis: Distinct Entity or Time Dependent Phenomena; Advanced Symptom Management Strategies in Multiple Sclerosis, Ethnic Considerations and Multiple Sclerosis Disease Variability; The Dynamics of the Gut Microbiome in Multiple Sclerosis in Relation to Disease; Spinal Cord Imaging in Relation to Clinical Status in Multiple Sclerosis, and more.

In this issue of MRI Clinics, guest editors Drs. Reza Forghani and Ashok Srinivasan bring their considerable expertise to the topic of Demyelinating and Inflammatory Lesions of the Brain and Spine. Top experts in the field provide multiple articles on multiple sclerosis, as well as articles on bacterial, fungal, and viral infections of the brain and spine. Contains 10 relevant, practice-oriented topics including demyelinating disease: NMO spectrum disorders and variants; toxic and drug-related white matter diseases of the brain and spine; bacterial and viral infectious diseases of the brain; bacterial and viral infectious diseases of the spine; multiple sclerosis: clinical update and clinically-oriented radiologic reporting; basic science of neuroinflammation and involvement of the inflammatory response in disorders of the nervous system; and more. Provides in-depth clinical reviews on demyelinating and inflammatory lesions of the brain and spine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.