Advanced Studies in Experimental and Clinical Medicine

Advanced Studies in Experimental and Clinical Medicine
Title Advanced Studies in Experimental and Clinical Medicine PDF eBook
Author P. Mereena Luke
Publisher CRC Press
Pages 310
Release 2021-03-22
Genre Medical
ISBN 1000093948

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This volume provides a selection of chapters on new developments in various areas of clinical medicine, including dental, surgery, and general practice. These scientific chapters analyze the diagnostic processes and inform of new and novel diagnostic techniques. This book is divided into two sections; the first section contains review papers and includes an overview of experimental and clinical medicine, explaining its history to modern times. The second section presents a selection of original research papers from respected authors on a variety of topics.

Advanced Studies in Experimental and Clinical Medicine

Advanced Studies in Experimental and Clinical Medicine
Title Advanced Studies in Experimental and Clinical Medicine PDF eBook
Author P Mereena Luke
Publisher Apple Academic Press
Pages 288
Release 2022-10
Genre
ISBN 9781774637708

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This volume, Advanced Studies in Experimental and Clinical Medicine: Modern Trends and Approaches, provides a selection of chapters on new developments in various areas of clinical medicine, including dental, surgery, and general practice.

Academy of Medical Sciences, USSR Plan of Scientific Research in the Field of Medicine in the USSR for the Years 1961-1962

Academy of Medical Sciences, USSR Plan of Scientific Research in the Field of Medicine in the USSR for the Years 1961-1962
Title Academy of Medical Sciences, USSR Plan of Scientific Research in the Field of Medicine in the USSR for the Years 1961-1962 PDF eBook
Author National Institutes of Health (U.S.)
Publisher
Pages 224
Release 1964
Genre
ISBN

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Handbook of Sleep Research

Handbook of Sleep Research
Title Handbook of Sleep Research PDF eBook
Author
Publisher Academic Press
Pages 758
Release 2019-06-21
Genre Science
ISBN 0128137444

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Handbook of Sleep Research, Volume 30, provides a comprehensive review of the current status of the neuroscience of sleep research. It begins with an overview of the neural, hormonal and genetic mechanisms of sleep and wake regulation before outlining the various proposed functions of sleep and the role it plays in plasticity, and in learning and memory. Finally, the book discusses disorders of sleep and waking, covering both lifestyle factors that cause disrupted sleep and psychiatric and neurological conditions that contribute to disorders. - Emphasizes a comparative and multidisciplinary approach to the topic of sleep - Covers the neurobiology and physiology of sleep stages, mechanisms of waking, and dreaming - Discusses in detail the proposed functions of sleep, from health and rest, to memory consolidation and synaptic plasticity - Examines the current state of research in mammalian and non-mammalian species, ranging from primates to invertebrates

Research in Progress at the University of Minnesota, July 1924-July 1925

Research in Progress at the University of Minnesota, July 1924-July 1925
Title Research in Progress at the University of Minnesota, July 1924-July 1925 PDF eBook
Author
Publisher
Pages 320
Release 1926
Genre Research
ISBN

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Bibliographical Series

Bibliographical Series
Title Bibliographical Series PDF eBook
Author University of Minnesota
Publisher
Pages 460
Release 1925
Genre
ISBN

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Small Clinical Trials

Small Clinical Trials
Title Small Clinical Trials PDF eBook
Author Institute of Medicine
Publisher National Academies Press
Pages 221
Release 2001-01-01
Genre Medical
ISBN 0309171148

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Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.