Acute Lung Injury and Repair
Title | Acute Lung Injury and Repair PDF eBook |
Author | Lynn M. Schnapp |
Publisher | Humana Press |
Pages | 188 |
Release | 2016-11-07 |
Genre | Medical |
ISBN | 3319465279 |
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.
Acute Lung Injury
Title | Acute Lung Injury PDF eBook |
Author | Geoffrey J. Bellingan |
Publisher | John Wiley & Sons |
Pages | 154 |
Release | 2000 |
Genre | Animal welfare |
ISBN | 9789051995039 |
This book provides a comprehensive and up to date picture of the molecular mechanisms underlying acute lung injury, focusing both on the mechanisms of injury and of repair. Topics covered include the cells involved, their injurious products including pro-inflammatory cytokines, proteases and free radical species as well as the fibrotic response and its molecular regulation, the role of the immune system, airway repair and remodelling and transcription factors regulating inflammation. All the chapters are written by experts in their field and reflect the lecture given by these authors at a recent international meeting also entitled " Acute lung injury: from inflammation to repair", held as part of the ongoing Molecular Pathology Annual symposia at University College London. The meeting gathered together a wide range of scientists and clinicians all of whom are at the cutting edge of inflammation and repair as it relates to acute lung injury. It is the breadth of approach that makes the volume so useful.
Ventilator-Induced Lung Injury
Title | Ventilator-Induced Lung Injury PDF eBook |
Author | Didier Dreyfuss |
Publisher | CRC Press |
Pages | 776 |
Release | 2006-03-21 |
Genre | Medical |
ISBN | 1420019260 |
This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Cons
Etiology and Treatment of Acute Lung Injury
Title | Etiology and Treatment of Acute Lung Injury PDF eBook |
Author | Sadis Matalon |
Publisher | IOS Press |
Pages | 320 |
Release | 2001 |
Genre | Lungs |
ISBN | 9781586031831 |
This book contains contributions of internationally known basic scientists and clinicians with expertise in various aspects of lung injury and repair. This monogram on the pathophysiology and treatment of Acute Lung Injury contains five different sections, each one with contributions from both basic and clinical scientists, outlining existing controversies, an how they can be resolved by future multidisciplinary studies. The various sections discuss: sodium transport and fluid clearance across the normal and injured lungs, the role of the pulmonary surfactant in the pathogenesis and treatment of ARDS, mechanisms and modification of acute and chronic lung injury, ventilatory strategies for the management of acute respiratory distress syndrome and nitric oxide: friend or foe.
Lung Injury
Title | Lung Injury PDF eBook |
Author | Robert H. Notter |
Publisher | CRC Press |
Pages | 888 |
Release | 2005-04-20 |
Genre | Medical |
ISBN | 9780824757939 |
Progressing from general scientific principles and concepts to in-depth topical discussions of current research and treatment methods, this comprehensive reference defines the cellular and molecular mechanisms contributing to inflammatory lung injury and repair. Extensive coverage is provided on key mediators and pathways important in acute and chronic pulmonary inflammation and lung injury, as well as the mechanistic pathophysiology of related diseases ranging from clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) to idiopathic pulmonary fibrosis (IPF) and other subacute and chronic conditions. Additional chapters also address vascular dysfunction, surfactant dysfunction, reactive oxygen/nitrogen species, and cell and animal models of acute and chronic lung injury.
Lung Injury
Title | Lung Injury PDF eBook |
Author | Ronald G. Crystal |
Publisher | Lippincott Williams & Wilkins |
Pages | 424 |
Release | 1992 |
Genre | Medical |
ISBN |
A comprehensive review of lung injury, defence and repair and therapeutic interventions. The text focuses on clinically relevant issues such as infections and host defences, immune injury, airborne contaminants, acute lung injury, injury from drugs, fibrotic processes and genetic modulation.
The Alveolar Epithelium
Title | The Alveolar Epithelium PDF eBook |
Author | Michael Kasper |
Publisher | |
Pages | 222 |
Release | 2020-09-23 |
Genre | |
ISBN | 9783039431663 |
Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.