Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

This user-friendly text presents current scientific information, diagnostic approaches, and management strategies for the care of children with acute and chronic respiratory diseases. A consistent chapter format enables rapid and effortless location of the most current protocols on manifestations, etiologies, triggers, approaches to treatment, complications, and preventative strategies. Includes guidance on differential diagnosis to help determine which disease or condition the patient may have. Uses extensive color-coded algorithms to facilitate quick diagnosis, management, and treatment decisions. Provides the latest scientific information and diagnostic and management strategies for the care of children with respiratory illnesses. Presents cutting-edge coverage with new information on the biology of, and the influences on, the respiratory system during childhood, as well as the diagnosis and management of both common (ie, wheezing infant, cystic fibrosis, tuberculosis) and.

A convenient compact textbook that fits snugly into your scrubs pocket. Developed at McMaster University, the birthplace of evidence-based medicine (EBM) and one of the world's top universities, in cooperation with over 300 highly renowned scientists from North America and Poland.

Microbes – can’t live with them, can’t live without them. Increasingly, we’re finding out that our microbiota (the microbes that live on us) are essential for our wellbeing – they provide us with nutrients and vitamins and play a key role in developing our immune system. On the other hand, they are responsible for a great deal of misery, as they are major causes of death and debility around the world. As well as our own microbiota turning against us, there are lots of other microbes out in the wider world that can seriously damage, or even kill, those they infect. The current pandemic of COVID-19 shows the devastating effect that an infectious disease can have – our lives have been turned upside down. If you live in a developed country, you’re not likely to get killer diseases such as ebola and cholera, but you do have a high chance of catching other infections that can have a significant impact on your wellbeing. This book focuses on those infections you’re most likely to go down with, and supplies the answers to the following questions about them: Which infectious diseases are we likely to come across? How common are they? What microbes cause them? What happens to our bodies during an infection? How are the resulting illnesses treated? How can we avoid getting them? This book covers nearly 60 infectious diseases that people living in developed countries are likely to experience at some point during their life. It also has an introductory chapter that describes, in everyday language, the basic principles of microbiology and infectious diseases. Each chapter is lavishly illustrated, has interesting, relevant inserts, and provides a list of web-accessible suggestions for further reading.

The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.