At a time of increased interest and renewed shock over the Tuskegee syphilis experiments, Acres of Skin sheds light on yet another dark episode of American medical history. In this disturbing expose, Allen M. Hornblum tells the story of Philadelphia's Holmesburg Prison.

From 1951 until 1974, Holmesburg Prison in Philadelphia was the site of thousands of experiments on prisoners conducted by researchers under the direction of University of Pennsylvania dermatologist Albert M. Kligman. While most of the experiments were testing cosmetics, detergents, and deodorants, the trials also included scores of Phase I drug trials, inoculations of radioactive isotopes, and applications of dioxin in addition to mind-control experiments for the Army and CIA. These experiments often left the subject-prisoners, mostly African Americans, in excruciating pain and had long-term debilitating effects on their health. This is one among many episodes of the sordid history of medical experimentation on the black population of the United States. The story of the Holmesburg trials was documented by Allen Hornblum in his 1998 book Acres of Skin. The more general history of African Americans as human guinea pigs has most recently been told by Harriet Washington in her 2007 book Medical Apartheid. The subject is currently a topic of heated public debate in the wake of a 2006 report from an influential panel of medical experts recommending that the federal government loosen the regulations in place since the 1970s that have limited the testing of pharmaceuticals on prison inmates. Sentenced to Science retells the story of the Holmesburg experiments more dramatically through the eyes of one black man, Edward “Butch” Anthony, who suffered greatly from the experiments for which he “volunteered” during multiple terms at the prison. This is not only one black man’s highly personal account of what it was like to be an imprisoned test subject, but also a sobering reminder that there were many African Americans caught in the viselike grip of a scientific research community willing to bend any code of ethics in order to accomplish its goals and a criminal justice system that sold prisoners to the highest bidder.

During the Cold War, an alliance between American scientists, pharmaceutical companies, and the US military pushed the medical establishment into ethically fraught territory. Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.

Just prior to World War II, an appalling event will occur in a Philadelphia prison that will augur the murderous mayhem that is about to befall the civilized world. Thrown into a criminal maelstrom - the discovery of eight bizarrely discolored inmate corpses - is an unschooled county coroner who owes his job to an unscrupulous mayor and a political machine that ensured his election. For Heshel Glass the choice is clear: confirm a fictitious police account of the inmate deaths or follow the dictates of his conscience and initiate an unprecedented "blue-ribbon inquest" to explore the probability that recalcitrant prisoners were cooked alive by sadistic prison guards and heartless administrators.

Shining a light on the deadly health consequences of incarceration. Finalist in the PROSE Award for Best Book in Anthropology, Criminology, and Sociology by the Association of American Publishers Kalief Browder was 16 when he was arrested in the Bronx for allegedly stealing a backpack. Unable to raise bail and unwilling to plead guilty to a crime he didn't commit, Browder spent three years in New York's infamous Rikers Island jail—two in solitary confinement—while awaiting trial. After his case was dismissed in 2013, Browder returned to his family, haunted by his ordeal. Suffering through the lonely hell of solitary, Browder had been violently attacked by fellow prisoners and corrections officers throughout his incarceration. Consumed with depression, Browder committed suicide in 2015. He was just 22 years old. In Life and Death in Rikers Island, Homer Venters, the former chief medical officer for New York City's jails, explains the profound health risks associated with incarceration. From neglect and sexual abuse to blocked access to care and exposure to brutality, Venters details how jails are designed and run to create new health risks for prisoners—all while forcing doctors and nurses into complicity or silence. Pairing prisoner experiences with cutting-edge research into prison risk, Venters reveals the disproportionate extent to which the health risks of jail are meted out to those with behavioral health problems and people of color. He also presents compelling data on alternative strategies that can reduce health risks. This revelatory and groundbreaking book concludes with the author's analysis of the case for closing Rikers Island jails and his advice on how to do it for the good of the incarcerated.

Prolonged solitary confinement has become a widespread and standard practice in U.S. prisons—even though it consistently drives healthy prisoners insane, makes the mentally ill sicker, and, according to the testimony of prisoners, threatens to reduce life to a living death. In this profoundly important and original book, Lisa Guenther examines the death-in-life experience of solitary confinement in America from the early nineteenth century to today’s supermax prisons. Documenting how solitary confinement undermines prisoners’ sense of identity and their ability to understand the world, Guenther demonstrates the real effects of forcibly isolating a person for weeks, months, or years. Drawing on the testimony of prisoners and the work of philosophers and social activists from Edmund Husserl and Maurice Merleau-Ponty to Frantz Fanon and Angela Davis, the author defines solitary confinement as a kind of social death. It argues that isolation exposes the relational structure of being by showing what happens when that structure is abused—when prisoners are deprived of the concrete relations with others on which our existence as sense-making creatures depends. Solitary confinement is beyond a form of racial or political violence; it is an assault on being. A searing and unforgettable indictment, Solitary Confinement reveals what the devastation wrought by the torture of solitary confinement tells us about what it means to be human—and why humanity is so often destroyed when we separate prisoners from all other people.

The modern classic of race and medicine updated with an additional chapter on the Tuskegee experiment's legacy in the age of AIDS.