The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.

Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "hard data" to support therapeutic and diagnostic modalities.

Musical Creativities in Practice explores the social and the cultural contexts in which creativity in music occurs. It begins by considering what constitutes creativity - taking a cross cultural view of music, while investigating creative processes far beyond just the classical music genre - including electronic media, popular music, and improvised music. In addition it looks at creativity in both writing and performing. The field of musical education is a key focus - examining why creativity is important within the educational environment, and looking at how schools might sometimes stifle creativity in their music teaching, rather than encourage it. The book is packed with case studies and real-life examples taken from studies across the world, providing a powerful corrective to myths and outmoded conceptions which privilege the creative practice of individual artists. Musical Creativity in Practice argues the need for conceptual expansion of musical creativities in line with vital contemporary real world practices. It explores how different types of musical creativities are recognised and communicated in the real world practices of a diversity of professional musicians. The book covers creative practice issues underlying composing, improvising, singer songwriting, originals bands, DJ cultures, live coding and interactive sound designing and the implications of creativity research for music education and for the assessment of creativities in industry and education. Musical Creativities in Practice will be valuable for those in fields of music psychology and music education, from advanced undergraduate level upwards.

First Published in 2008. Routledge is an imprint of Taylor & Francis, an informa company.