Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases. This book examines lipid peroxidation as a current and future biomarker of oxidative stress.

Phytochemicals are receiving increasing attention due to their observed nutritional and health-promoting effects in numerous food applications. As plant secondary metabolites with bioactive properties, they may provide desirable health benefits beyond basic nutrition to reduce chronic disease conditions. Their importance in nutrition and health cannot be overstated as it has generated so much interest and studies focused on elucidating their roles has produced so many outstanding results. Plant phytochemicals are readily used in alternative medicine in South East Asia especially, in China and India and they are becoming widely acceptable worldwide. However, very little is still known about the phytochemicals despite these intense research efforts because of their diverse biological and chemical nature. In this newest addition to the series, Nutraceuticals: Basic Research and Clinical Applications, Plant Food Phytochemicals and Bioactive Compounds in Nutrition and Health provides a comprehensive review of the current state of knowledge in the field of bioactive plant phytochemical compounds, their food sources, bioactivities, bioavailability, extraction, production, and applications. Experts in the field discuss various bioactivities of the notable and promising plant phytochemicals of significance in nutrition and health, e.g., lowering of CVD, hypertension, cholesterol, diabetes, obesity, inflammation, cancer, oxidative stress, neurodegenerative diseases and a host of other chronic disease conditions. Key Features: Describes the various nutritional and bioactive significances of notable and promising plant phytochemicals of significance in nutritional and medical research and their food and/or plant sources Includes various approaches for the quantification, extraction and production of the notable and promising phytochemical compounds in nutrition and health Examines the challenges and promises of plant phytochemical as ingredients for the development of functional foods and nutraceuticals as well as their use in alternative medicine Discusses regulatory issues regarding plant phytochemicals, especially as it pertains to their health claims and use

Trusted for more than 40 years and updated to reflect today’s nursing challenges, Porth’s Pathophysiology: Concepts of Altered Health States, 11th Edition, continues a legacy of excellence with a comprehensive, nursing-focused approach that instills a mastery of both the physical and psychological aspects of altered health. More approachable and inclusive than ever, this unique text clarifies complex ideas through diverse perspectives, the latest evidence-based information, and engaging in-text features and application exercises.

Unlock the mysteries of ascorbic acid in Ascorbic Acid - Biochemistry and Functions, a groundbreaking exploration into the multifaceted world of this essential nutrient. Authored by renowned experts in the field, this book transcends traditional boundaries, offering a deep dive into the biochemical intricacies, health implications, and diverse applications of ascorbic acid. Organized around six main themes, the book commences with a broad overview of general features and the biological role of ascorbic acid. From there, it takes readers on a journey through the intricacies of ascorbic acid deficiency, exploring its health effects and proposing preventive measures. The antioxidant roles and functions of ascorbic acid are unraveled, shedding light on its pivotal contribution to cellular health and disease prevention. Not stopping at the basics, the book extends its reach to unconventional applications. From the modulatory effects of inhaled ascorbic acid on the immune system to its potential role in sepsis treatment and preventive measures against neurodegenerative diseases, each chapter adds a unique dimension to the reader’s understanding. Tailored for students, researchers, and professionals in biochemistry, medicine, and nutrition, this book equips readers with a comprehensive toolkit to navigate the intricate landscape of ascorbic acid. Bridging the gap between theory and application, it serves as an invaluable resource for those seeking a profound comprehension of the subject. Ascorbic Acid - Biochemistry and Functions is not just a book; it is a roadmap through the dynamic terrain of one of nature’s essential compounds. Whether you are delving into the scientific underpinnings or exploring its diverse applications, this book promises to be your guide in unraveling the secrets of ascorbic acid. Embark on a transformative journey into the heart of this vital nutrient and discover its profound impact on human health and well-being.

Oxidative stress plays a crucial role in the pathophysiology of various diseases when there is a disruption of the intracellular redox balance and the homeostatic balance between cellular oxidants and antioxidants. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) react with molecular targets including proteins, lipids, and nucleic acids contributing to mitochondrial injury and cellular dysfunction. This book intends to provide the readers with an extensive overview of the novel approaches and prospects based on oxidative and nitrosative stress in the pathophysiology of various diseases and in the current treatment strategies with antioxidants.

Autoxidation of unsaturated lipids has received much attention because it has many applications in the rancidity of foods and stability of lipids in biological tissues and compartments. This book reviews state-of-the-art developments in the understanding of the oxidation of lipids and its connection with the oxidation of other biological molecules such as proteins and starch. The various chapters illustrate the special features associated with different lipids, antioxidants, reaction conditions, and lipids environments. The material in this book provides a better understanding of lipid oxidation pathways.

Oxygen-Ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classical biochemistry, physiological and pharmacological knowledge. Ozone is an oxidizing molecule, a sort of super active oxygen, which, by reacting with blood components generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting the chronic oxidative stress present in atherosclerosis, diabetes and cancer. Moreover, by inducing nitric oxide synthase, ozone therapy may mobilize endogenous stem cells, which will promote regeneration of ischemic tissues. The description of these phenomena offers the first comprehensive picture for understanding how ozone works and why. When properly used as a real drug within therapeutic range, ozone therapy does not only does not procure adverse effects but yields a feeling of wellness. Half the book describes the value of ozone treatment in several diseases, particularly cutanious infection and vascular diseases where ozone really behaves as a “wonder drug”. The book has been written for clinical researchers, physicians and ozone therapists, but also for the layman or the patient interested in this therapy.