The Global Polio Eradication Strategy 2022-2026 supersedes the Polio Strategy 2019-2023, taking into account new tools and approaches, including the novel oral polio vaccine type 2 and need to more concertedly address vaccine-derived polioviruses, as well as new operations tactics in light of the ongoing COVID-19 pandemic. It is intended to layout the roadmap to achieving and sustaining a polio-free world, free of all forms of poliovirus. It is intended to be a strategic resource and guidance document for GPEI stakeholders, partners, donors and affected country governments.