Durable left ventricular assist device (LVAD) technology is advancing at a rapid pace with increasing reliability of mechanical circulatory support for progressively longer periods. With more patients living longer on their LVAD as destination therapy or until eventual heart transplantation, concomitant valvular disease will have a greater impact on outcomes and patient quality of life. While some valvular lesions exist prior to LVAD implantation, others develop de novo from continuous flow mechanical support physiology. The presence of valvular disease in the setting of LVAD support is known to reduce effective cardiac output, increase left ventricular and atrial pressure, and increase right ventricular afterload. These hemodynamic changes can in turn contribute to right heart failure and negatively impact patient outcomes.

With every update, Mac OS X grows more powerful, more dependable, and easier to use--and Mac OS X Tiger is no exception. But along with the new features come fresh issues--new areas to troubleshoot, new functionality to unravel, and new glitches waiting to confound even the savviest Mac users. Not to worry. Best-selling author and Mac guru Ted Landau turns his diagnostician's eye on Mac OS X Tiger, arming readers with fix-it knowledge This popular fix-it classic offers more troubleshooting information, tips, and hacks than any other single volume. Chock-full of detailed, understandable advice for maintaining and troubleshooting Mac OS X Tiger, this comprehensive reference is where users will turn before they head to the repair shop. Readers will find solutions for every Mac OS X problem under the sun plus the technical grounding they need to turn a diagnostic eye on their own operating systems. Filled with tips, tools, and preventive measures, the guide includes in-depth coverage of Library directories and folders, file and font maintenance, crash prevention and recovery, and more.

The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.

This book follows the concept of perceiving the entire aorta as one functional organ assuming that all individual pathologies and local interventional procedures affect the up- and downstream segments with consequences for complications and disease progression. Thus any preventive or surgical strategy must recognize the aortic disease in its entirety. The book intends to cover the full spectrum of aortic pathologies, mechanisms and functional interplay. The latest available diagnostic tools and options for surgical treatment are presented by the foremost experts in their field in state-of-the-art reviews. The reader is provided with the most current and comprehensive insight into all fundamental and clinical aspects of aortic disease. All chapters are carefully complemented with figures and illustrations.

This book provides comprehensive, state-of-the art insights into aortic valvuloplasty. Aortic valve repair is a relatively new procedure. Since first being successfully performed in the 1990s was objectively assessed in the 2000s, this procedure has now become standardized, reproducible, and popular around the globe. Written by experts in surgery and cardiology and richly illustrated, it discusses the aspects of anatomy, pathophysiology, diagnosis and surgical procedure that are essential for successful repair. Contributing to the popularization and development of aortic repair, it is a valuable resource for surgeons, cardiologists, cardio-anesthetists and paramedical staff interested in the field and will be good resource for popularizing and developing aortic valve repair.

An essential source of reference for this linguistic community, as well as for linguists working on typology and syntax.