A perfect journal for anyone! A pure and simple lined journal / notebook with a cute and funny phrase on the front and all at a very low price for a decent gag gift. 6 x 9 in size 120 blank pages to deface as required Great eye catching cover. Buy one for your favorite co-worker, friend, husband, wife, partner or just about anyone who enjoys a good laugh!

This Awesome Appreciation Journal / Notebook makes the IDEAL appreciation gift for any family members or friends. This Cute notebook features 110 blank pages and is 6 x 9 inches in size.

The author, a computer science professor diagnosed with terminal cancer, explores his life, the lessons that he has learned, how he has worked to achieve his childhood dreams, and the effect of his diagnosis on him and his family.

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T cell engager ( BITES), Dual Variable Domain ( DVD), Chimeric Antigen Receptor - Modified Tcells (CART) that are currently being used as therapeutic agents for immunology and oncology disease conditions. In addition to other pharmaceuticals and biopharmaceuticals, all these novel formats are fragile with respect to their stability/structure under processing conditions meaning marginal stability in the liquid state and often require lyophilization to enhance their stability and shelf-life. This book contains chapters/topics that will describe every aspect of the lyophilization process and product development and manufacturing starting from the overview of lyophilization process, equipment required, characterization of the material, design and development of the formulation and lyophilization process, various techniques for characterization of the product, scale-up/tech-transfer and validation. It also describes the application of CFD coupled with mathematical modeling in the lyophilization process and product development, scale-up, and manufacturing. Additionally, Principles and Practice of Lyophilization Process and Product Development contains an entire dedicated section on “Preservation of Biologicals” comprised of nine chapters written by experts and including case studies.

Doctoral Thesis / Dissertation from the year 2010 in the subject Engineering - Geotechnology, , course: Civil Engineering, language: English, abstract: With growing infrastructure developments in hilly areas and due to economical constraints of using locally available rockfill materials for construction of embankments, practicing engineers must be acquainted with geotechnical response of non-conventional granular soils. These materials are most likely to disintegrate with time due to physical and chemical weathering. In general, the laboratory investigations on durability characteristics of such materials are only made through simple slaking tests. However, studies examining the effects of slaking-induced disintegration of soil grains on the geotechnical engineering analysis and design parameters are rather limited. This is essentially due to the reason that the grains of standard laboratory sands are mostly durable and hence, the stress-strain response is considered to be unaffected by the presence of water. In order to explore the possible effects of deterioration of soil grains on static and dynamic properties of granular soils, a series of consolidated drained torsional shear tests on various crushed soft rocks were performed under saturated and dry conditions and compared with a well reported Toyoura silica sand consisting of durable grains. Due to the sensitivity of crushed rockfill to deteriorate upon water-submergence, test under dry conditions represented the response of a soil with intact grains, whereas a similar test under saturated condition simulated the potential reduction in strength and stiffness of the soil with time. From the grain size distributions determined after each test, a degradation index was defined to quantify the degree of disintegration of grains. Strength and deformation properties determined from monotonic as well as cyclic shear tests were then compared with this index. Possible correlations of water-induced deterioration of soil grains with consolidation behaviour, peak shear strengths, friction angles, dynamic shear stiffness, and volume-change characteristics during shearing were explored. In addition, the effects of confining stress and shear strain level on particle breakage were also investigated. It was concluded that time-dependent characterization of rockfill materials by monitoring the degree of deterioration can be helpful to avoid catastrophic geotechnical failures. Nonetheless, this study is a caution to conventional soil mechanics in which decay of grains and loss of soil strength with time are often uncared.

The definitive history of America’s greatest incubator of innovation and the birthplace of some of the 20th century’s most influential technologies “Filled with colorful characters and inspiring lessons . . . The Idea Factory explores one of the most critical issues of our time: What causes innovation?” —Walter Isaacson, The New York Times Book Review “Compelling . . . Gertner's book offers fascinating evidence for those seeking to understand how a society should best invest its research resources.” —The Wall Street Journal From its beginnings in the 1920s until its demise in the 1980s, Bell Labs-officially, the research and development wing of AT&T-was the biggest, and arguably the best, laboratory for new ideas in the world. From the transistor to the laser, from digital communications to cellular telephony, it's hard to find an aspect of modern life that hasn't been touched by Bell Labs. In The Idea Factory, Jon Gertner traces the origins of some of the twentieth century's most important inventions and delivers a riveting and heretofore untold chapter of American history. At its heart this is a story about the life and work of a small group of brilliant and eccentric men-Mervin Kelly, Bill Shockley, Claude Shannon, John Pierce, and Bill Baker-who spent their careers at Bell Labs. Today, when the drive to invent has become a mantra, Bell Labs offers us a way to enrich our understanding of the challenges and solutions to technological innovation. Here, after all, was where the foundational ideas on the management of innovation were born.

NEW YORK TIMES BESTSELLER • A stunning “portrait of the enduring grace of friendship” (NPR) about the families we are born into, and those that we make for ourselves. A masterful depiction of love in the twenty-first century. NATIONAL BOOK AWARD FINALIST • MAN BOOKER PRIZE FINALIST • WINNER OF THE KIRKUS PRIZE A Little Life follows four college classmates—broke, adrift, and buoyed only by their friendship and ambition—as they move to New York in search of fame and fortune. While their relationships, which are tinged by addiction, success, and pride, deepen over the decades, the men are held together by their devotion to the brilliant, enigmatic Jude, a man scarred by an unspeakable childhood trauma. A hymn to brotherly bonds and a masterful depiction of love in the twenty-first century, Hanya Yanagihara’s stunning novel is about the families we are born into, and those that we make for ourselves. Look for Hanya Yanagihara’s latest bestselling novel, To Paradise.