Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

A complete set of best practices, tools, and techniques for turning conversations into a rich source of business information Many organizations are now recognizing that the untapped knowledge of their members can be used to benefit every aspect of their business, from making smarter and faster decisions to improving products and efficiency. This book offers a clear-cut road map for building a successful knowledge management system to capture and fully exploit the knowledge exchanged in conversations. Written by two of the foremost experts in online communities, this book covers a set of best practices, tools, and techniques for using conversation and online interaction to provide affordable and effective knowledge-based benefits and solutions. With a unique and invaluable perspective, the authors offer guidance for collecting, capturing, and cataloging knowledge so that it can be used to improve efficiency and reduce costs in areas ranging from internal procedures through customer relations and product development. This book provides step-by-step solutions for developing an effective knowledge network, including how to: * Formulate strategies and create action plans * Select the right tools for peer-to-peer networks, interactive communities, and events * Work with legacy systems * Train staff and stimulate participation * Improve productivity and measurement criteria The companion Web site contains templates, checklists, a discussion board, and links to software.

How does a telecommunications company function when its right hand often doesn't know what its left hand is doing? How do rapidly expanding, interdisciplinary organizations hold together and perform their knowledge work? In this book, Clay Spinuzzi draws on two warring theories of work activity - activity theory and actor-network theory - to examine the networks of activity that make a telecommunications company work and thrive. In doing so, Spinuzzi calls a truce between the two theories, bringing them to the negotiating table to parley about work. Specifically, about net work: the coordinative work that connects, coordinates, and stabilizes polycontextual work activities. To develop this uneasy dialogue, Spinuzzi examines the texts, trades, and technologies at play at Telecorp, both historically and empirically. Drawing on both theories, Spinuzzi provides new insights into how net work actually works and how our theories and research methods can be extended to better understand it.

Empires of Knowledge charts the emergence of different kinds of scientific networks – local and long-distance, informal and institutional, religious and secular – as one of the important phenomena of the early modern world. It seeks to answer questions about what role these networks played in making knowledge, how information traveled, how it was transformed by travel, and who the brokers of this world were. Bringing together an international group of historians of science and medicine, this book looks at the changing relationship between knowledge and community in the early modern period through case studies connecting Europe, Asia, the Ottoman Empire, and the Americas. It explores a landscape of understanding (and misunderstanding) nature through examinations of well-known intelligencers such as overseas missions, trading companies, and empires while incorporating more recent scholarship on the many less prominent go-betweens, such as translators and local experts, which made these networks of knowledge vibrant and truly global institutions. Empires of Knowledge is the perfect introduction to the global history of early modern science and medicine.

Introducing the basic concepts in total program control of the intelligent agents and machines, Intelligent Internet Knowledge Networks explores the design and architecture of information systems that include and emphasize the interactive role of modern computer/communication systems and human beings. Here, you’ll discover specific network configurations that sense environments, presented through case studies of IT platforms, electrical governments, medical networks, and educational networks.

This book presents more than four decades of research in international business at the Department of Business Studies, Uppsala University. Gradually, this research has been recognized as 'The Uppsala School'. The work in Uppsala over the years reflects a broad palette of issues and approaches.