This book contains the most comprehensive coverage available anywhere for two-level factorial designs. The re-analysis of 50 published examples serves as a how-to guide for analysis of the many types of full factorial and fractional factorial designs. By focusing on two-level designs, this book is accessible to a wide audience of practitioners who use planned experiments.

Any prior information an experimenter has should be incorporated into the design of further experiments. Assume such information is expressed as probabilities that each parameter of the full factorial model is nonzero. This report develops optimal design procedures by posing the experimental design problem as a finite decision problem. Bays and mini-max design strategies are then derived and their application illustrated. The major computational step is the evaluation of all possible matchings of physical variables to the abstract variables of all potential designs. The technique of telescoping sequences of blocks permits the consideration of experiments to be performed in stages.

This carefully edited collection synthesizes the state of the art in the theory and applications of designed experiments and their analyses. It provides a detailed overview of the tools required for the optimal design of experiments and their analyses. The handbook covers many recent advances in the field, including designs for nonlinear models and algorithms applicable to a wide variety of design problems. It also explores the extensive use of experimental designs in marketing, the pharmaceutical industry, engineering and other areas.

"This is an engaging and informative book on the modern practice of experimental design. The authors' writing style is entertaining, the consulting dialogs are extremely enjoyable, and the technical material is presented brilliantly but not overwhelmingly. The book is a joy to read. Everyone who practices or teaches DOE should read this book." - Douglas C. Montgomery, Regents Professor, Department of Industrial Engineering, Arizona State University "It's been said: 'Design for the experiment, don't experiment for the design.' This book ably demonstrates this notion by showing how tailor-made, optimal designs can be effectively employed to meet a client's actual needs. It should be required reading for anyone interested in using the design of experiments in industrial settings." —Christopher J. Nachtsheim, Frank A Donaldson Chair in Operations Management, Carlson School of Management, University of Minnesota This book demonstrates the utility of the computer-aided optimal design approach using real industrial examples. These examples address questions such as the following: How can I do screening inexpensively if I have dozens of factors to investigate? What can I do if I have day-to-day variability and I can only perform 3 runs a day? How can I do RSM cost effectively if I have categorical factors? How can I design and analyze experiments when there is a factor that can only be changed a few times over the study? How can I include both ingredients in a mixture and processing factors in the same study? How can I design an experiment if there are many factor combinations that are impossible to run? How can I make sure that a time trend due to warming up of equipment does not affect the conclusions from a study? How can I take into account batch information in when designing experiments involving multiple batches? How can I add runs to a botched experiment to resolve ambiguities? While answering these questions the book also shows how to evaluate and compare designs. This allows researchers to make sensible trade-offs between the cost of experimentation and the amount of information they obtain.

"The eighth edition of Design and Analysis of Experiments continues to provide extensive and in-depth information on engineering, business, and statistics-as well as informative ways to help readers design and analyze experiments for improving the quality, efficiency and performance of working systems. Furthermore, the text maintains its comprehensive coverage by including: new examples, exercises, and problems (including in the areas of biochemistry and biotechnology); new topics and problems in the area of response surface; new topics in nested and split-plot design; and the residual maximum likelihood method is now emphasized throughout the book"--