"Study Interventions: Participants in the placebo group received standard lifestyle recommendations. Participants in the metformin group received standard lifestyle recommendations along with metformin 850 mg twice daily. Participants in the lifestyle group were given an intensive lifestyle modification program taught by case managers on a one-to-one basis with the goal of achieving and maintaining a 7% or greater reduction in body weight, improvements in dietary intake, and physical activity of at least 150 minutes per week. The lifestyle modification program was taught during 16 sessions over a 24-week period, and reinforced with individual (usually monthly) and group sessions after that"--

50 Studies Every Internist Should Know presents key studies that shape today's practice of internal medicine. Selected using a rigorous methodology, the studies cover topics including: preventative medicine, endocrinology, hematology and oncology, musculoskeletal diseases, nephrology, gastroenterology, infectious diseases, cardiology, pulmonology, geriatrics and palliative care, and mental health. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

50 Studies Every Palliative Doctor Should Know presents key studies that have shaped the practice of palliative medicine. Selected using a rigorous methodology, the studies cover topics including: palliative care, symptom assessment and management, psychosocial aspects of care and communication, and end-of-life care. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

This title presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation, shock, ARDS, nutrition, renal failure, trauma, infection, diabetes, and physical therapy

50 Studies Every Ophthalmologist Should Know presents key studies that have shaped the practice of ophthalmology. Selected using a rigorous methodology, emphasis has been placed on landmark studies which have influenced current ophthalmology practice guidelines. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for ophthalmologists, especially those in training or preparing for board review, as well as anyone who wants to learn more about the data behind clinical practice.

50 Studies Every Psychiatrist Should Know presents key studies that have shaped the practice of psychiatry. Selected using a rigorous methodology, the studies cover topics including: psychotic disorders, depressive disorders, women's mental health, child and adolescent disorders, and epidemiological studies. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

50 Studies Every Pediatrician Should Know presents key studies that have shaped the current clinical practice of pediatrics. Selected using a rigorous methodology, the studies cover topics including: allergy immunology, behavioral, cardiology, dermatology, endocrinology, ENT, general pediatrics, hematology, infectious disease, neonatology, nephrology, neurology, oncology, ophthalmology, orthopedics, and pulmonary. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This is one of the only books of its kind to present a collection of the most influential clinical trials in pediatrics that are detailed enough to be used on rounds, but still easily digestible.