MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. Forewords by: Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989 and Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs

This revolutionary and best-selling resource contains more than 200 pages of additional information and expanded discussions on zeolites, bitumen, conducting polymers, polymerization reactors, dendrites, self-assembling nanomaterials, atomic force microscopy, and polymer processing. This exceptional text offers extensive listings of laboratory exercises and demonstrations, web resources, and new applications for in-depth analysis of synthetic, natural, organometallic, and inorganic polymers. Special sections discuss human genome and protonics, recycling codes and solid waste, optical fibers, self-assembly, combinatorial chemistry, and smart and conductive materials.

A beautiful book that reveals the world of art collecting from home, featuring exquisite examples of Hollingsworth and Morris family furniture. Start with House, Finish with a Collection is the story of how a couple's use of American art and antiques evolved from furnishing a house into a full-blown passion for collecting. Featuring exquisite examples of Hollingsworth and Morris family furniture, Weber boxes, Pennsylvania clocks and Kirk-Stieff silver, as well as American paintings by the Peale family, Edward Hicks, Edward Redfield and Horace Pippin, this museum-calibre collection reveals a pride in the early American sensibility. The combination of text and extraordinary photographs traces this remarkable journey and demonstrates that life can be more than comfortable living among these collections. The compendium catalogues the diversified and important collection, making this a valuable scholarly reference as well as a reading pleasure.