This book constitutes the refereed proceedings of the 10th International Conference on Culture and Computing, C&C 2022, held as part of the 23rd International Conference, HCI International 2022, which was held virtually in June/July 2022. The total of 1271 papers and 275 posters included in the HCII 2022 proceedings was carefully reviewed and selected from 5487 submissions. The C&C 2022 proceedings presents topics such as User Experience, Culture, and Technology, Culture and Computing in Arts and Music and preservation and fruition of cultural heritage, as well as developing and shaping future cultures.

This symposium is the first scientific event organized by the “Seminar for Epistemology” under the auspices of the University of Trieste. The aim of the symposium was to collect and open to discussion the contributions of a number of distinguished scientists from cognitive sciences and experimental nature sciences and to bring together specialists of various backgrounds.The very authoritative contributions presented at the Conference represent relevant, even if not exhaustive, specimens of the role of new conceptual tools in science.