Completely updated and revised, the 27th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children, including COVID-19. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. New in the 27th edition: Continuous updates of drug and dosing changes 4 new chapters Reorganized chapter order to improve functionality

Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. TOPICS INCLUDE Antimicrobial Therapy by Clinical Syndromes Antimicrobial Therapy for Neonates Choosing Among Antibiotics Antifungal Agents Antiviral Agents Antiparasitic Agents Oral Step-down Therapy for Serious Infections Prevention of Symptomatic Infection Approach to Antibiotic Allergies Antibiotic Stewardship New in the 28th Edition Updated recommendations on acute hematogenous osteomyelitis, based on newly published guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America, including information on a decrease in the incidence of MRSA infections, allowing the recommendation of cefazolin, again, in empiric therapy for most pediatric bone infections Updated recommendations on influenza treatment and prophylaxis, reflecting American Academy of Pediatrics guidance for 2021-2022 Ceftazidime/avibactam now preferred over fluoroquinolones for treatment of Klebsiella pneumoniae carbapenemase-producing enteric bacilli, if susceptible Cefiderocol, a new iron-binding siderophore cephalosporin class, recently approved in adults for treatment of many drug-resistant pathogens, particularly Acinetobacter, Stenotrophomonas, and Pseudomonas; under study in children New dosing for posaconazole suspension formulation New approaches to mucormycosis Added baloxavir for children 12+ years old Online updates of COVID-19 therapies once emergency use authorization in children at http://www.aap.org/nelsons Updated Nelson's app also available

An unrivaled reference tool for advanced practice providers and students in clinical practice settings This concise and easy-to-read drug therapy prescribing reference provides critical information for advanced practice nurses and physician assistants in clinical practice settings who are involved in the primary care management of patients with acute, episodic, and chronic health problems, life-altering and life-threatening diseases, and needs for health promotion and disease prevention. Interspersed with clinically useful information, such as monitored laboratory values, patient teaching points, and safety information, this reference draws upon data taken directly from FDA-approved drug labels and patient medication guides, and is organized by diagnosis rather than by drug classification, to provide advanced practice practitioners with the comprehensive, concise, and up-to-date information on drug therapies that they need to help achieve positive outcomes in their daily practice. The first section of this book presents drug treatment regimens for over 700 clinical diagnoses, listed alphabetically by generic name, followed by important information required for prescription decision-making. The second section provides additional information on treatment, organized in a convenient table format. An alphabetical cross-reference index of drugs allows for easy identification of alternate drug names and their location within the text. New to this Edition: Information on over 100 new diagnoses and over 100 new generic drugs indicated for the treatment of quality of life-altering and life-threatening conditions such as chronic kidney disease, genetic diseases, mesothelioma, MS, metastatic cancers, and rare diseases. Updates on drugs used for site-specific cancers, mental health issues, and commonly diagnosed diseases such as diabetes and asthma. Details on new drug approvals including indications, treatment regimens, adverse reactions, drug-drug interactions, warnings and precautions, and use in special populations Key Features: Provides new drug treatment regimens for drugs that are first in class, novel drugs, orphan drugs, new drugs with breakthrough or fast track designation and drugs with new indications and expanded social populations. Includes drug prescribing information on diseases prevalent outside of North America, including endemic diseases with known transmission and treatment interventions. Serves advanced practice providers across the United States and internationally. Consistent with approvals and recommendations for use by the FDA.

Completely updated and revised, the 30th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. Free updates are available at aap.org/Nelsons. New in the 30th Edition Updated multiple drug-resistant gram-negative pathogens treatment recommendations with newly approved antibiotics Newer antibiotics, beyond vancomycin, to treat MRSA infections Updates on children's influenza, COVID-19, and enterovirus treatments Updates on travelers' diarrhea Latest guidelines for treatment of invasive pediatric fungal infections New guidelines for treatment of pediatric bacterial arthritis Recommendations on hepatitis C virus and cytomegalovirus treatment options CHAPTERS INCLUDE Antimicrobial Therapy According to Clinical Syndromes Antimicrobial Therapy for Neonates Choosing Among Antibiotics Antifungal Agents Antiviral Agents Antiparasitic Agents Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens; Fungal Pathogens; Viral Pathogens; and Parasitic Pathogens Approach to Antibiotic Therapy for Drug-Resistant Gram-Negative Bacilli and Methicillin-Resistant Staphylococcus aureus Systemic and Topical Antimicrobial Dosing and Dose Forms Sequential Parenteral-Oral Antibiotic Therapy (Oral Step-Down Therapy) for Serious Infections Antimicrobial Prophylaxis/Prevention of Symptomatic Infection Approach to Antibiotic Allergies Antibiotic Stewardship Antibiotic Therapy for Children With Obesity And more...

This best-selling and widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices.

New 22nd Edition! Practical, evidence-based recommendations from the experts in antimicrobial therapy This widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. In response to growing concerns about overuse of antibiotics, the.

This book provides multidisciplinary reviews of the mechanism of action and uses of methotrexate in the treatment of cancer, psoriasis, gynecologic and inflammatory diseases. The intended audience is composed of clinicians involved in the care of patients suffering from oncologic, gynecologic, rheumatic diseases as well as scientists involved in research into the pathogenesis and treatment of these diseases. This book is unique in that it provides a single, state-of-the-art source for information regarding the mechanism and use of methotrexate in many different areas of medicine.