A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

This open access book offers a timely guide to challenges and current practices to permanently plug and abandon hydrocarbon wells. With a focus on offshore North Sea, it analyzes the process of plug and abandonment of hydrocarbon wells through the establishment of permanent well barriers. It provides the reader with extensive knowledge on the type of barriers, their functioning and verification. It then discusses plug and abandonment methodologies, analyzing different types of permanent plugging materials. Last, it describes some tests for verifying the integrity and functionality of installed permanent barriers. The book offers a comprehensive reference guide to well plugging and abandonment (P&A) and well integrity testing. The book also presents new technologies that have been proposed to be used in plugging and abandoning of wells, which might be game-changing technologies, but they are still in laboratory or testing level. Given its scope, it addresses students and researchers in both academia and industry. It also provides information for engineers who work in petroleum industry and should be familiarized with P&A of hydrocarbon wells to reduce the time of P&A by considering it during well planning and construction.

Provides an in-depth overview of the Federal Reserve System, including information about monetary policy and the economy, the Federal Reserve in the international sphere, supervision and regulation, consumer and community affairs and services offered by Reserve Banks. Contains several appendixes, including a brief explanation of Federal Reserve regulations, a glossary of terms, and a list of additional publications.

Natech Risk Assessment and Management: Reducing the Risk of Natural-Hazard Impact on Hazardous Installations covers the entire spectrum of issues pertinent to Natech risk assessment and management. After a thorough introduction of the topic that includes definitions of terms, authors Krausmann, Cruz, and Salzano discuss various examples of international frameworks and provide a detailed view of the implementation of Natech Risk Management in the EU and OECD. There is a dedicated chapter on natural-hazard prediction and measurement from an engineering perspective, as well as a consideration of the impact of climate change on Natech risk. The authors also discuss selected Natech accidents, including recent examples, and provide specific 'lessons learned' from each, as well as an analysis of all essential elements of Natech risk assessment, such as plant layout, substance hazards, and equipment vulnerability. The final section of the book is dedicated to the reduction of Natech risk, including structural and organizational prevention and mitigation measures, as well as early warning issues and emergency foreword planning. - Teaches chemical engineers and safety managers how to safeguard chemical processing plants and pipelines against natural disasters - Includes international regulations and explains how to conduct a natural hazards risk assessment, both of which are supported by examples and case studies - Discusses a broad range of hazards and the multidisciplinary aspects of risk assessment in a detailed and accessible style