This book is a comprehensive overview of the fungi that are clinically relevant for animals and humans. It is divided in three major parts: the first part comprises the history of veterinary and medical mycology, general aspects of morphology, growth, nutrition, reproduction and classification of fungi. In the second part, the etiologic agents of cutaneous, subcutaneous and systemic mycoses are described in detail with special emphasis on emerging and uncommon pathogenic fungi. Each chapter consists of a brief history and the morphology, classification, reproduction, susceptibility to disinfectants, natural habitat, distribution, genome, isolation, growth and colony characteristics, antigenic characteristics, virulence factors. The major diseases and their routes of transmission, pathogenesis, immunity, diagnosis and treatment are also covered. The third part focuses on laboratory diagnosis including clinical sample collection, their processing for fungal isolation, special stains for microscopic visualization, culture media composition and a relevant glossary. Each chapter includes color photographs, schematic diagrams and tables for better understanding.

Sure to be the veterinary student's favourite lab partner, this handy, easy-to-follow manual presents basic information about isolating and identifying fungi in the veterinary mycology laboratory. The authors, all teachers with years of experience in veterinary diagnostic microbiology, developed this handbook in the classroom and the laboratory. Their efforts reflect the real problems and situations that practising veterinarians encounter. Intended for use in conjunction with a comprehensive textbook, the manual offers guidelines for the collection and submission of specimens for fungal identification, outlining different procedures for cutaneous, subcutaneous, systemic, aquatic, and other common and opportunistic mycoses. It discusses the clinical syndromes, general diagnostic procedures, characteristics, and treatment of fungal agents of veterinary significance. The photographs, showing typical features of common disease-causing fungi, will enable students to identify these organisms in cultures and clinical samples. Clear and systematic in its approach, this manual will prove an indispensable companion to veterinarians as well as veterinary students.

Fungal pathogens pose an on-going and serious threat for poikilotherms and homeotherms, and can cause a broad spectrum of diseases ranging from innocuous to life-threatening. In addition, long-term exposure to some mycotoxigenic moulds can lead to mycotoxicoses in human and animals. Given the expanding population of immune compromised hosts, the list of fungal opportunists grows longer every year. Moreover, antifungal resistance, drug-related toxicity and our limited arsenal of antifungals have exacerbated the situation. To address these problems, strategies such as the identification of novel targets, use of the structure-activity relationship in rational drug design, development of new formulations, modification of existing antifungals to combat resistance, and bioavailability enhancement are called for. For the reader’s convenience, this book has been divided into three sections. The first six chapters of Section I provide a timely review of mycoses, from endemic to cosmopolitan and from generalized to specific, while both chapters of Section II focus on risks associated with mycotoxins. In closing, the two chapters of Section III describe potential antifungal leads and drug candidates based on phytochemicals and coumarin scaffold.

This book is the first to give a well-documented, illustrated survey of the historical background to disease caused by fungi in man and domesticated animals. Medical and veterinary mycology includes the study of infectious diseases caused by actinomycetes and allergic conditions induced by both fungi and actinomycetes, and their history is also described here. The foundations of medical mycology have been laid over the past centuries but have only been completed during recent decades. This is therefore an appropriate moment to write the history of this specialty, which involves the collaboration of medically qualified and non-medically trained workers. Dr Ainsworth's long and varied career in mycology fits him ideally to the task he has undertaken and he has drawn on his experience to provide an invaluable scholarly perspective on the area.

This new edition of a standard reference includes classical methods and information on newer technologies, such as DNA hybridization and monoclonal antibodies.