"My job isn't to revolutionize anything. My job is to give women a sense of relief, to acknowledge what they're struggling with." --Cathy Guisewite Like women around the globe, Cathy has been constantly puzzled by her romantic relationships. From Irving to Simon to Alex, the men in Cathy's life have provided a never-ending source of confusion and amusement ever since the strip began in 1976. "If men's hair falls out," our weary heroine laments, "it's because there's nothing in there for it to hold onto." It's no wonder, then, that cartoonist Cathy Guisewite's Cathy collection should be called Understanding the "Why" Chromosome. In this hilarious book, Cathy outdoes herself in witty revelations about men, food, Mom, and career: Cathy's four basic guilt groups. Cathy epitomizes the highs and lows felt by distaff women throughout the world. In Understanding the "Why" Chromosome, Cathy's found a new challenge: a boyfriend who's a decade younger than she. Fitness fanatic Alex, who's sensitive and not particularly ambitious, introduces Cathy to an entirely new relationship angst, then introduces her to his hip, young mother. Cathy's baffled by the age difference, but is just as stumped when he proposes. "What's wrong with our relationship the way it is now? "she wails when Alex finally pops the question. Throughout her trials and tribulations, Cathy's friends keep her sane. There's happily married Charlene, the office loudspeaker; exhausted Andrea, mother of Zenith and Gus; her well-meaning mom and dad; Cathy's unrealistic boss Mr. Pinkley; and bouncy little Electra, Cathy's canine alter ego. Her frequent and frustrating shopping excursions also give rise to an enormous wave of female recognition "Skip the clothes and just shove a Stairmaster through the curtain," Cathy deadpans. Cathy Guisewite is an enormously talented cartoonist who has won numerous awards for her strip and animated television shows. Her countless fans trust Cathy to constantly express the right blend of humor and observation almost as if she had x-ray vision into the human condition.

One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

This topic has been realized, and is in collaboration with Dr. Constanze Pentzold, Post Doctoral Researcher at the Institute of Human Genetics, University Hospital Jena.

This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.

“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.