Sam Bullit is running for Mayor of New York City on an anti-Spider-Man campaign, and Daily Bugle Editor-in-Chief J. Jonah Jameson is backing him 100%. But who is pulling Bullit's strings? None other than the Kingpin of Crime! Collects Ultimate Spider-Man (2000) #46-53.

Collects Amazing Spider-Man #794-796, Annual #42 and material from Amazing Spider-Man (2015) #25. Nearly a year ago, Spider-Man hurled the dangerous madman called Zodiac a full year into the future. That means Zodiac’s had a whole year to prepare for their rematch! And when the web-slinger pays Doctor Strange’s Sanctum Sanctorum a visit looking for a consult, he finds there’s a new Sorcerer Supreme in town: Loki! And this newest Master of the Mystic Arts has his own unique brand of magic! Meanwhile, Norman Osborn has scoured the globe for a cure to the genetic tampering that prevents him from becoming the Green Goblin — and at long last, he’s about to find it! Plus: Betty Brant searches for answers when she receives a voicemail from her late husband, Ned Leeds! All this and the uncanny threat of Clash!

Collects Amazing Spider-Man (2018) #37-43. Spider-Man can’t be in four places at once — or can he?! Peter Parker’s life is as complicated as ever, but is science the answer? Meanwhile, J. Jonah Jameson starts his new life as a podcast host — and his first guest is Spider-Man! JJJ and Spidey have been on pretty good terms for a while now, so it’s only fitting that “Jolly” Jonah would sabotage all that and put the entire city in danger, right? Plus: The wall-crawler must roll the dice in the Palace, the new super villain casino run by none other than Chance! And Spidey’s odds don’t look good. But while Peter’s life gets ever crazier, what’s Boomerang up to? And what does it have to do with Mayor Kingpin?

Spider-Man is as amazing as ever against adversarial alumni like the Lizard and the Kingpin, as well as up-and-coming enemies such as Stegron and Jigsaw - with the lesser-known larcenies of the Big Wheel and the Spider-Squad to fill his spare time! Featuring the first appearances of Rocket Racer and Will O' the Wisp! Forgotten chapters from the Green Goblin legacy and the Clone Saga! Spider-Man's origin and Peter Parker's college graduation! And J. Jonah Jameson at his best and worst! Guest-starring the Punisher, Nova the Human Rocket, the Human Torch and the X-Men! Collecting AMAZING SPIDER-MAN (1963) #161-185 and ANNUAL #11, GIANT-SIZE SPIDER-MAN #6, and NOVA (1976) #12.

Spider-Man is pitted against one of his most deadly enemies in the shape of the Green Goblin, as the flying felon tries to defeat the webbed wonder once and for all.

Driven by a desire for revenge, Spider-Man sets out to take down Wilson Fisk, the infamous Kingpin of Crime, who employed the man who killed Peter's beloved Uncle Ben. Collects Ultimate Spider-Man (2000) #8-13.

Collects Amazing Spider-Man (1999) #509-514. Holy! Looks like-! It can't be...is it? A stunning new evil emerges to stalk Peter Parker as the biggest Spider-Man event in years rocks the wall-crawler's world! The worst defeat that Peter Parker ever endured - a moment frozen in the minds of Spider-Man fans everywhere - was supposed to be far in his past. But now, two villains - ripped, perhaps, directly from that very moment - have emerged and they threaten to destroy everything that he holds dear!