Kaoru and Kaori are superpowered twins, the product of an unhinged, unethical maker. Their shadowy past merges with Hitsugi's own origins, a burden she carries as heavily as the coffin on her back. But Hitsugi is breaking free of her past and committing herself to doing Black Label's good work. The first order of business: wiping out a pair of red-haired blemishes on the face of the city!

A new, unknown jet injector is lose in the city, sowing the seeds of chaos and death. The humans she infects turn into frothing, raving white-haired maniacs driven to torture and kill. And what's worse--anyone who comes into close contact with these monsters is liable to become one themselves. Tatara and Suzue are in trouble--will Black Label reach them in time!?

Black Label has always been glad to have Sayo Hitsugi's fearsome strength on their side, but as she rampages through Black Label's high security wards, they're starting to appreciate just how much! While Sagiri is prepared to stop her comrade by any means necessary, is Arashi on the same page...?

As their adversary grows more aggressive, Black Label is forced to take drastic action. Bypassing the chaos of the streets above, the survivors are led through deep underground tunnels to the safety of Mochizuki Hospital-the heart of Black Label itself! Risking their organization's exposure may be the only way to save the city, but with Reika Togo's whereabouts and intentions still a mystery, the risk may be greater still...!

With Mikoto and Oriha still at the mercy of Syringe agents, Arashi reluctantly teams up with Chikage, and the two race to rescue their friends. So far, Chisa Yuki has maintained her innocent act in front of the other survivors, but the moment she turns bloodthirsty, Black Label won't be the only ones who suffer...

While Black Label is locked in a stalemate with Syringe, D breaks ranks to confront Arashi. Though Arashi is reluctant to let his personal grudge distract him from the larger disaster at hand, the threat against Kominato is too great to ignore. Arashi’s past and future priorities converge in this final confrontation with the terrorist D!!

Mochizuki General Hospital boasts some of the most well-trained (and well-endowed) nurses in town. But though these ladies spend much of their day battling sickness, their after-hours are spent fighting a very different sort of disease...Under the leadership of the hospital chairman, a handful of staff members and local teenagers form a group of mercenary assassins, targeting the "cancers" of society and excising those individuals before their wickedness spreads.